卵巢成熟囊性畸胎瘤恶变  

MALIGNANT TRANSFORMATION OF MATURE CYSTIC TERATOMA OF THE OVARY

作　　者：富琪[1] 魏丽惠[1] 回允中[1] 薛卫成[1] 虞幸[1] 

机构地区：[1]北京医科大学人民医院妇科

出　　处：《北京医科大学学报》1998年第3期261-263,共3页Journal of Peking University(Health Sciences)

摘　　要：目的：探讨卵巢成熟囊性畸胎瘤恶变的治疗方法及预后。方法：对２０年卵巢成熟囊性畸胎瘤恶变１１例进行回顾性分析。结果：卵巢成熟囊性畸胎瘤恶变占良性畸胎瘤的１．４％，其中鳞癌变７例（７／１１），腺癌变３例（３／１１），卵巢甲状腺肿恶变１例（１／１１）。５年平均生存率８０％，Ⅰ期为１００％，Ⅱ～Ⅲ期为０。结论：卵巢囊性畸胎瘤囊壁厚度大于１ｃｍ时，可疑恶变，应送冰冻病理检查；治疗以手术为主，加用化疗或放疗；早期患者预后明显好于中晚期；Objective: To investigate the treatment and prognosis of malignant transformation of mature cystic teratoma (MCT) of the ovary. Methods: 11 cases of the last 20 years were analyzed retrospectively. Results: Malignant transformation of MCT amounted to 1.4% of all MCT. Of the 11 cases, 7(7/11) were squamous cell carcinoma, 3(3/11) adenocarcinoma, and 1 (1/11) malignant struma ovarii. The overall 5year survival rate was 80%. For the patients of stage Ⅰ, 5year survival rate was 100%, but for stage Ⅱ-Ⅲ, none. Conclusion: It would be better for clinicians to pay attention to the thickness of the wall of the cystic teratoma. If it is more than 1 cm, frozen section should be done. The malignant transformation of mature cystic teratoma should be treated by operation, followed by chemotherapy or radiotherapy. The prognosis of the patients of stage Ⅰ was obviously better than those of stage Ⅱ-Ⅲ. The prognosis of malignant struma ovarii is usually good.

关 键 词：卵巢肿瘤 病理学 畸胎癌 腺癌 鳞状上皮癌 

分 类 号：R737.31[医药卫生—肿瘤]