血糖及糖化血红蛋白检测与急性脑梗死患者临床关系的研究  

Study on the relationship between blood glucose,glycosylated hemoglobin and clinical relation in patients with acute cerebral infarction

作　　者：梁存福[1] 

机构地区：[1]临沂市人民医院脑科医院干部病房,山东临沂276000

出　　处：《华夏医学》2009年第2期189-191,共3页Acta Medicinae Sinica

摘　　要：目的:研究血糖、糖化血红蛋白水平与急性脑死塞患者的临床关系。方法:219例急性脑梗死患者在入院24h内空腹或静脉输液前测血糖及糖化血红蛋白。在病情好转或血糖正常后复查头颅CT,计算梗死灶体积。分别将血糖及糖化血红蛋白升高组的神经功能缺损、临床疗效、梗死灶大小与血糖及糖化血红蛋白正常组进行比较。结果:急性脑梗死患者血糖升高组、糖化血红蛋白升高组比血糖正常组梗死灶大、好转率低、死亡率高。结论:高血糖尤其糖化血红蛋白升高会增加急性脑梗死神经系统损伤,梗死灶大,临床疗效不良。故积极预防和治疗高血糖是预防脑梗死的有效措施。Objective：To study the blood glucose,glycosylated hemoglobin and clinical relation in patients with acute cerebral infarction, Methods ：The blood glucose and glycosylated hemoglobin of 219 cases of acute cerebral infarction were measured fasting 24 hours within admission or before intravenous infusion. After improvement of the condition or the blood glucose being normal, reviewed the brain CT, and calculated the size of the infarct lesion. The neurolog- ical deficit, clinical efficacy and infarct lesion size between high blood glucose, glyeosylated hemoglobin group and the normal one were compared. Results ：The infarct lesion size of high blood glucose and glycosylated hemoglobin group was larger, the improving rate were lower and the death rate was higher than that of the normal group. Conclusion： High blood glucose and glyeosylated hemoglobin would cause the increasing nervous system deficit, larger infarct lesion and poor clinical effect. Active prevention and treatment of high blood glucose is one of the effective measures of preventing cerebral infarction.

关 键 词：脑梗死 血糖 糖化血红蛋白 预后 

分 类 号：R743.33[医药卫生—神经病学与精神病学]