症状性肝海绵状血管瘤经栓塞治疗后碘油沉积状态与瘤体缩小率的关系  

The Relationship between Lipiodol Deposition Status and Tumor＇s Minification of Symptomatic Cavernous Hemangioma of Liver after Interventional Therapy

作　　者：曾庆乐[1] 陈勇[1] 赵剑波[1] 朱桥华[1] 李彦豪[1] 

机构地区：[1]南方医科大学南方医院介入治疗科,广东广州510515

出　　处：《实用放射学杂志》2009年第6期869-872,共4页Journal of Practical Radiology

摘　　要：目的探讨症状性肝海绵状血管瘤（SCHL）经栓塞治疗后碘油沉积状态差异的原因及与瘤体缩小率的关系。方法89例SCHI，进行平阳霉素碘油乳剂肝动脉硬化性栓塞（PLE—IASE）。平阳霉素（PYM）剂量2．0～24mg（9．8mg±4．4mg），超液化碘油（LP）剂量1．5～20ml（5．9ml±2．9m1），平阳霉素碘油乳剂（PLE）剂量3～40ml（11．8ml±5．9m1）。按照栓塞后病灶内碘油沉积范围是否超过瘤体直径的1／3作为判定碘油沉积状态良好与否的标准，所有患者栓塞后对碘油沉积状态进行分类，随访（22．8±6．5）月，记录各自瘤体缩小率并进行差异比较。结果本研究PLE—IASE治疗技术成功率98．9％。89例SCHL栓塞后碘油沉积状态良好64例（71．9％），不良25例（28．1％）。碘油沉积状态良好者瘤体缩小率为（0．56±0．22）％，不良者瘤体缩小率为（O．23±0．27）％。统计学分析显示碘油沉积状态良好者瘤体缩小率比沉积不良者高，差异有显著性意义（t值-5．835，P=0．000）。结论PLE—IASE治疗SCHL时碘油沉积良好者瘤体缩小较不良者明显。Objective To search the reasons of difference in lipiodol deposition status of symptomatic cavernous hemangioma of liver{SCHL）and its relationship to the tumor＇s minification after embolization therapy . Methods 89 patients with SCHL underwent pingyangmycin--lipiodol emulsion intraarterial sclerosing embolization （ PLE--IASE } . The Pingyangmycin （ PYM } dosage was 2.0-24 mg （9.8 mg±4.4mg）, lipiodol[LP） was 1. 5-20 ml （5.9 ml±2. 9 ml）, and pingyangmycin--lipiodol emulsion （PLE） was 3~40 ml （11.8 ml±5.9 ml）. The lipiodol deposition status after embolization was judged according to the following criterion： the status was fine if the lipiodol deposition region exceed 1/3 of the tumor＇s diameter, otherwise it was not. All the patients were classified based on the above criterion. All cases were followed for （22.8±6.5） months. Results The successful rate of PLE--IASE was 98.9 %. LP deposition was fine in 64 cases（71.9%） and not good in 25 patients. The minification rate of the tumors in good lipiodol deposition was [ 0.56± 0.22 ）% and （ 0.23 ±0.27 ）% in bad deposition, there was significant difference in statistics between both（t= 5. 835,P= 0. 000）. Conclusion The lipiodol deposition in SCHL after PLE--IASE is effective on the degree of tumor＇ s minification.

关 键 词：海绵状血管瘤 肝 超液化碘油 沉积 

分 类 号：R735.7[医药卫生—肿瘤] R815[医药卫生—临床医学]