单鼻孔蝶窦入路显微手术治疗垂体腺瘤  

Treatment of pituitary adenomas via endonasal transsphenoidal approach

作　　者：刘小红[1] 陈明振[1] 李少鹏[1] 王云彦[2] 宋敏鹰[1] 陈伟朝[1] 陈伟轩[1] 谭明轩[1] 陈永生[1] 

机构地区：[1]东莞市人民医院神经外科,广东东莞523000 [2]山东大学齐鲁医院神经外科,山东济南250012

出　　处：《中国热带医学》2009年第7期1302-1303,共2页China Tropical Medicine

摘　　要：目的探讨经蝶入路治疗垂体腺瘤临床意义。方法2000年9月～2008年9月共收治垂体腺瘤患者63例,术前均进行垂体冠状CT重建、MRI动态增强扫描,内分泌学检查。所有患者均经单鼻孔蝶窦入路显微手术肿瘤切除。随访3～36个月。结果肿瘤全切51例,次全切8例,部分切除4例。术后症状及内分泌检查改善60例,5例出现并发症,包括鼻黏膜感染,一过性脑脊液鼻漏,垂体功能低下。4例1年后复发。结论经蝶手术治疗垂体腺瘤创伤小,操作简单,安全,肿瘤切除完全,住院时间短,费用低。Objective To explore the chnical significance of treatment of pituitary adnomas via endonasal transsphenoidal approach. Methods From September 2000 to September 2008,63 cases of pituitary adenoma were treated by endonasal transsphenoidal approach ,all the patients received coronal CT scan and reconstructive image,enhanced and movable MRI scan,endocrinological examinations before the operation.AU patients got a follow-up of 3-36 months. Results The tumor removal was total in 50 cases,subtofl in9 cases,and partal in 4 eases. All 60 patients achieved an improvement in clinical and endocrinology.5 cases had postoperative complications,including nasal mucosal inflammation , eerebrespinal fluid rhinorrhea and pituitary disfunetion .4 cases had rdaps at 1 year after the operation. Conclusion The treatment of pituitary adnomas via endonasal transsphenoidal approach is minimal invasiveness,simple operation,safety, lowcost and relatively complete resection of tumor, shorter hospitalization time.

关 键 词：垂体腺瘤 经蝶入路 显微手术 

分 类 号：R736.4[医药卫生—肿瘤]