液基薄片与传统手工涂片在肺肿瘤诊断的比较研究  

Comparative analysis of conventional smear and thin prepcytology test method in diagnosis of lung cancer

作　　者：刘慕嫦[1] 顾莹莹[1] 何萍[1] 杨通[1] 林云恩[1] 莫明聪[1] 何新明[1] 

机构地区：[1]广州医学院第一附属医院病理科,广东广州510000

出　　处：《中国热带医学》2009年第7期1354-1355,共2页China Tropical Medicine

摘　　要：目的探讨新柏液基薄层细胞学技术(Thin Prepcytology Test,TCT)与传统手工涂片在肺肿瘤诊断中的价值。方法收集疑似肺癌患者的痰液标本,采用TCT及传统普通细胞涂片法检查,并对两组结果进行比较。结果与传统涂片相比,采用TCT技术制片细胞多且集中,薄层均匀,背景干净,痰液标本及支气管针吸标本的肺肿瘤的阳性检出率有所提高,与传统涂片法联合应用阳性检出率进一步提高。结论采用TCT技术检测痰液细胞学与支气管针吸标本可获高质量涂片,能提高肺肿瘤的诊断率,是值得推广的一种新技术,与传统涂片法联合应用具有重要的临床价值。Objective To compare the value of new thin prepcytology test （TCT） with the conventional manual smear in the diagnosis of lung cancer. Methods There 66 sputum samples and 57 aspiration-needle biopsy specimen from lung cancer patients by surgically and pathologically confirmed were collected. Thin prepeytology test and conventional smear examinations were performed and compared in diagnosis of lung cancer. Results Compared with that of conventional smear method, there smaller area of smear membrane, clearer background, more distinctly cytologic picture and stereoscopic ones by TCT. The diagnostic rate for lung cancer by TCT was significantly higher than that by conventional smear method （P〈0.05）. The diagnostic rate for lung cancer was obviously enhanced in combined detection by the two methods,. Conclusion TCT method is superior to conventional smear. The value of diagnosis of lung cancer would be enhanced by combination of the two methods.

关 键 词：液基薄层细胞学技术 传统手工涂片 肺肿瘤 比较 

分 类 号：R734.2[医药卫生—肿瘤]