准分子激光手术前后角膜形态及其波面像差的变化分析  

The variation analysis of corneal topography and wavefront aberrations before and after excimer laser surgery

作　　者：王小园[1] 金敏[1] 周传清[2] 

机构地区：[1]广州市第一人民医院眼科,510180 [2]上海交通大学激光与光子生物医学研究所

出　　处：《临床眼科杂志》2009年第3期198-200,共3页Journal of Clinical Ophthalmology

摘　　要：目的研究准分子激光近视矫正前后角膜波面像差的变化及其与视觉效果的关系。方法对欲接受准分子激光原位角膜磨镶术(LASIK)治疗的230例(440只眼)进行术前、术后1年的角膜地形图、视力和对比敏感度检查,获得角膜形态、角膜波面像差及视觉效果的数据,进行统计分析。结果术前角膜具有扁长形状,非球面系数和角膜顶点半径具有正相关性(P<0.001)。术前的角膜像差和视力、对比敏感度水平没有相关性(P>0.05),而术后这种相关性存在于角膜像差和对比敏感度之间(P<0.01),但不存在于角膜像差和视力之间(P>0.05)。结论角膜形态和瞳孔中心位置对角膜高阶像差具有明显的影响作用,在设计个性化激光手术时必须考虑这些个性化的参数。Objective To investigate the change of corneal wavefront aberration and the relationship between cor- neal wavefront aberration with visual outcome in myopic eyes undertaken excimer laser refractive surgery. Methods This study include 230 patients （440 eyes） underwent laser in situ keratomileusis （ LASIK ）. Corneal topography, uncorrected visual acity and contrast sensitivity function were examined before and 1 year after LASIK. The cornea shape, the cornea wavefront were performed. Results The preoperative cornea has prolate shape, the aspheric coefficient and vertex radius of cornea has the positive correlation （ P 〈 0.001 ）. The preoperative cornea aberration and uncorrected visual acuity, contrast sensitivity level does not have the relevance （ P 〉 0.05 ）, the relevance of postoperation exists between the corneal aberration and the contrast sensitivity （ P 〈 0.01 ）, But does not exist between the cornea aberration and the uncorrected visual acuity （ P 〉 0. 05 ）. Conclusion The cornea shape and the position of the pupil center have the obvious effect to the highorder aberration of cornea, customized parameters must be considered while designing the customized excimer laser refractive surgery.

关 键 词：准分子激光术 角膜形态 波面像差 

分 类 号：R779.63[医药卫生—眼科] R772.2[医药卫生—临床医学]