角膜板层切除加结膜瓣覆盖术联合氟康唑治疗真菌性角膜炎  

Treatment of fungal keratitis by corneal lamellar resection plus conjunctiva cover combind with fluconazole

作　　者：张海霞[1] 程丹富[1] 张丽[1] 惠丰荷[1] 

机构地区：[1]山东省日照市人民医院眼科,276826

出　　处：《临床眼科杂志》2009年第3期258-259,共2页Journal of Clinical Ophthalmology

摘　　要：目的观察角膜板层切除加结膜瓣覆盖术联合氟康唑治疗真菌性角膜炎的临床效果。方法对23例(23只眼)真菌性角膜炎采用病灶区角膜板层切除,取上方桥状或蒂状球结膜瓣覆盖病灶区并缝合固定,瓣下涂入氟康唑药粉,1个月后在表面麻醉下剪断结膜蒂,并拆线。结果23只眼角膜炎全部控制,拆线时角结膜完全愈合。4个月至2年随访,视力眼前数指～0.1者18只眼,0.2～0.5者5只眼。所有移植的结膜瓣均为半透明愈合,血管萎缩,大部分角膜表面凹陷明显变浅。结论本手术方法为一种治疗真菌性角膜炎的有效方法之一。Objective To evaluate the effect of corneal lamellar resection plus conjunctiva cover combind with fluconazole for fungal keratitis. Metheds The corneal lamella of focus was resected and covered with pedicled conjunctival flap and fixed up by suture,then fluconazole powder was smeared under the conjunctival flap. The conjunctival pedicle was sniped with surface anaesthesia and removed the suture after one month. Results Keratifis of 23 eyes was eontroled, conjunctiva and cornea were healed up entirely when suture removed. Following-up 4 months to 2 years ,vision acuity of 18 eyes was CF-0. 1,5 eyes was 0.2 -0.5. All of conjunctival flaps was translucent in healing up,blood vessels were atrophic,and most hollows of corneal surface became shallow. Conclusion This measure was one of efficient ways for treatment of fungal keratitis.

关 键 词：真菌性角膜炎 角膜 结膜 氟康唑 手术 

分 类 号：R779.6[医药卫生—眼科]