急性脑梗死患者血清中Hcy、hs-CRP的研究  

Research on determination of serum Hcy and hs-CRP levels in patients with acute cerebral infarction

作　　者：白伟利[1] 

机构地区：[1]河南安阳地区医院神经二科,安阳455000

出　　处：《中国实用神经疾病杂志》2009年第10期23-24,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的研究急性脑梗死(ACI)患者治疗前后血清同型半胱氨酸(Hcy)和超敏C-反应蛋白(hs-CRP)水平的变化与意义,以及二者与脑梗死面积大小的关系。方法应用化学发光法和免疫比浊法对180例ACI患者治疗前后进行血清Hcy和hs-CRP水平测定。结果在治疗前ACI患者血清中,Hcy、hs-CRP水平显著高于正常人(P<0.05),二者治疗前、后相比亦有显著性差异(P<0.05),且与梗死灶面积呈显著正相关(P<0.05)。结论ACI患者血清Hcy和hs-CRP水平可反映ACI患者的脑梗死状态,对判断病情和预后有重要价值。Objective To investigate the changes of serum Hcy and hs-CRP levels after treatment in patients with acute cerebral infarction,and the relationships between both of them and the size of the infarction. Methods Serum Hcy（with chemi- luminescence）and hs-CRP（with immunoturbidity method） levels in 180 patients with cerebral infarction were detected before and after treatment. Resnlts Before treatment, serum Hcy and hs-CRP levels were significantly higher in the patients than those in controls（P〈0. 05）. After treatment,the serum Hcy,hs-CRP levels were also significantly different from those before treatment（P〈0. 05）. Moreover,the levels were positively correlated with the size of the infarction（P〈0.05）. Conclusion Detection of serum Hcy and hs-CRP levels was helpful for the perdiction of treating efficacy.

关 键 词：急性脑梗死 同型半胱氨酸 超敏C反应蛋白 

分 类 号：R743.33[医药卫生—神经病学与精神病学]