血浆纤维蛋白原水平与脑出血继续出血的关系  

Relationship between plasma fibrinogen level and hematoma enlargement after intracerebral hemorrhage

作　　者：李刚[1] 禇晓凡 饶宜光[1] 邹良玉[1] 

机构地区：[1]暨南大学第二临床学院神经内科,深圳518020

出　　处：《中国实用神经疾病杂志》2009年第11期32-34,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨血浆纤维蛋白原水平减低是否为脑出血继续出血的独立预测因素。方法对住院的227例脑出血患者进行评价,其中46例为脑出血继续出血患者,分析血浆纤维蛋白原水平与脑出血继续出血的关系。结果在校正传统脑出血继续出血危险因素后,与无继续出血的患者相比,有继续出血的患者发病到首次CT时间更短(3.5±1.9 vs 4.5±2.6,P=0.008),血浆纤维蛋白原水平更低(2.74±1.12 vs 3.10±0.82,P=0.048)。结论脑出血患者血浆纤维蛋白原水平与脑出血继续出血独立相关。Objective To investigate whether the decreased plasma fibrinogen level is an independent predictor of hemato- ma enlargement in patients with cerebral hemorrhage. Methods Two hundred and twenty-seven patients with cerebral hemorrhage hospitalized were evaluated, and 46 cases of them had hematoma enlargement. The relationship between plasma fibrinogen level and hematoma enlargement after intracerebral hemorrhage was analyzed. Results After adjusting risk factors of traditional hematoma enlargement, the time from onset to first CT-scan in patients with hematoma enlargement was significantly shorter than that of patients without hematoma enlargement （3.5±1.9 vs 4.5±2.6, P = 0. 008）, and plasma fibrinogen level was significantly decreased （2.74±1.12 vs 3.10±0. 82, P=0. 048） . Conclusion Plasma fibrinogen level is independently associated with hematoma enlargement after cerebral hemorrhage.

关 键 词：脑出血继续出血 纤维蛋白原 

分 类 号：R743.34[医药卫生—神经病学与精神病学]