骨显像加做颅骨侧位对鼻咽癌颅底骨侵犯的临床价值:与CT比较  

Value of additional skull lateral static imaging in whole-body bone imaging for skull bone invasion evaluation in nasopharyngeal carcinoma patients:comparison with CT

作　　者：冯会娟[1] 欧阳伟[1] 刘金华[1] 刘伟英[1] 

机构地区：[1]南方医科大学珠江医院核医学科,广东广州510282

出　　处：《南方医科大学学报》2009年第6期1216-1218,1222,共4页Journal of Southern Medical University

摘　　要：目的旨在探讨颅骨局部加位对NPC颅底骨侵犯的诊断价值并与CT进行对比。方法选取2003年01至2007年12月间病理确诊为NPC的放疗前患者,共405例,均在1周内行前后位全身骨显像(WBI)及颅骨左、右侧位局部显像和CT检查。结果WBI诊断与CT诊断阳性符合率29.48%,阴性诊断符合率76.05%,总符合率81.23%;骨局部显像目测诊断同CT诊断的阳性符合率67.95%,阴性诊断符合率74.07%,总符合率87.16%;骨局部显像半定量分析诊断同CT诊断的阳性符合率75.64%,阴性诊断符合率74.07%,总符合率88.64%。在27例CT诊断阴性而局部显像半定量分析诊断阳性的患者中,其中有9例同时行了MRI检查,MRI结果为阳性。结论全身骨显像加做局部颅骨侧位显像,对NPC颅底骨侵犯有较好的诊断价值,可做为鼻咽癌颅底骨侵犯的筛选方法。Objective To investigate the value of the additional skull lateral static imaging in whole-body bone imaging （WBI） vs CT for evaluation of skull base invasion in patients with nasopharyngeal carcinoma, Methods A total of 405 patients with pathologically confirmed NPC underwent WBI with additional static imaging of the left and right skull as well as CT examination of the nasopharynx and skull base within one week before the radiotherapy. Results The concordance rates between WBI and CT for positive and negative diagnosis were 29.48% and 76.05% in these cases,-respectively, with the total concordance rate of 81.23%. The concordance rates between skull lateral static imaging with visual judgment and CT examination for positive and negative diagnosis were 67.95% and 74.07%, respectively, showing a total concordance rate of 87.16%. Skull lateral static imaging with semi-quantitative analysis and CT examination showed concordance rates for positive and negative diagnosis of 75.64% and 74.07%, respectively, with a total rate of 88.64%. In 27 patients with negative diagnosis by CT but a positive one in skull lateral static imaging with semi-quantitative analysis, 9 had a positive diagnosis by magnetic resonance imaging. Conclusion Skull lateral static imaging can be of value in the diagnosis of skull base invasion in NPC patients and may serve as an effective means for screening skull base invasion in NPC.

关 键 词：鼻咽肿瘤 颅骨侧位显像 全身骨显像 颅底骨侵犯 

分 类 号：R739.63[医药卫生—肿瘤]