奥曲肽联合硝酸甘油治疗肝硬化静脉曲张出血的疗效分析  

The curative effect analysis of combining glycerol trinitrate and octreotide for the treatment of liver cirrhosis varicosis hemorrhage

作　　者：向志勇[1] 郑勇[1] 徐丽红[1] 李睿[1] 周婷[2] 杨远[2] 杨小艳[3] 

机构地区：[1]石河子大学医学院第一附属医院消化内科,新疆石河子832000 [2]石河子大学医学院第一附属医院医学实验室,新疆石河子832000 [3]石河子大学医学院第一附属医院老年病科,新疆石河子832000

出　　处：《临床肝胆病杂志》2009年第3期217-218,共2页Journal of Clinical Hepatology

摘　　要：目的观察奥曲肽联合硝酸甘油对肝硬化静脉曲张出血患者的疗效。方法选择120例肝硬化静脉曲张患者,随机分为二组,治疗组60例,给予奥曲肽联合硝酸甘油为主的治疗,对照组60例给予以奥曲肽为主的治疗。治疗2周,观察其疗效。结果治疗前后两组患者门静脉血流量的降低值和脾静脉血流量降低值比较有显著性差异;两组治愈率,平均止血时间及疗效差别比较具有统计学意义(P<0.05)。结论奥曲肽联合硝酸甘油治疗组治疗肝硬化静脉曲张出血的疗效优于单用奥曲肽的治疗组。Objective To observe the clinical effectiveness of combining glyce - rol trinitrate and octreotide for the treatment of liver cirrhosis varicosis hemorrhage. Methods one hundred and twenty（120） patients with liver cirrhosis and varicosis hemorrhage were randomized allocated into two groups. Treatment group： 60 patients, combining glycerol trinitrate and oetreotide for the treatment of liver cirrhosis and varicosis hemorrhage. Control group： 60 patients, with oetreotide for the treatment of liver cirrhosis and varicosis hemorrhage, two weeks were one course of treatment. Results Significant difference were exhibited between the treatment group and control group patients＇ step clown value of the blood flow of portal vein and splenic vein. with cure rate and average haemostasis time, significant difference were exhibited between two groups （P 〈 0. 05 ）. Conclusion combining glycerol Trinitrate and octreotide forthe patients with liver cirrhosis and varicosis hemorrhage showed a better resuh .

关 键 词：肝硬化静脉曲张 奥曲肽 硝酸甘油 

分 类 号：R575.2[医药卫生—消化系统]