前列地尔对急性胰腺炎患者血浆D-二聚体的影响  

Effects of PGE1 on D-dimer in patients with acute pancreatitis

作　　者：刘震[1] 沈洪亮[1] 张建表[1] 

机构地区：[1]上海市浦东新区人民医院消化内科,上海201200

出　　处：《临床医学》2009年第6期100-101,共2页Clinical Medicine

摘　　要：目的研究急性胰腺炎(AP)患者使用前列地尔治疗前后D-二聚体变化及前列地尔对AP患者的治疗意义。方法将65例急性胰腺炎患者随机分为两组,治疗组32例,对照组33例。对照组给予常规治疗,治疗组在常规治疗基础上应用前列地尔10μg加入0.9%生理盐水100ml中静脉滴注,每日1次连续7d,治疗前及7d后检测患者血浆D-二聚体水平。结果前列地尔治疗后治疗组较对照组D-二聚体水平明显降低,且差异有统计学意义(P<0.01)。结论前列地尔可通过改善微循环状态对AP患者具有一定的治疗作用。Objective To investigate the effects of PGE1 on D - dimer in patients with acute pancreatitis（AP）. Methods Sixty - five patients with AP were randomly divided into two groups ： PGE1 group 32 cases, control group 33 cases. Control group were treated with conventional therapy, in intervention group received PGE1 intravenous infusion （10 μg, once daily）in addition to conventional therapy. Before and after treatment of 1 week,the plasma levels of D - dimer was measured. Results The plasma levels of D - dimer in PGE1 group after treatment was significantly lower than control group after treatment （ P 〈 0.01 ）. Conclusion The PGE1 have treatment effect in AP patient circulatory disorder.

关 键 词：急性胰腺炎 前列地尔 D-二聚体 

分 类 号：R576[医药卫生—消化系统]