儿童鼻腔鼻窦骨化纤维瘤  

Ossifying fibroma of nasal cavity and sinus in children

作　　者：宋善芳[1] 陈雪松[1] 黄鹏[1] 李朝辉[1] 邓元新[1] 王洪田[1,2] 

机构地区：[1]山东省滨州市中心医院耳鼻咽喉头颈外科,山东滨州251700 [2]解放军总医院耳鼻咽喉头颈外科,北京100853

出　　处：《中国耳鼻咽喉头颈外科》2009年第6期320-322,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的提高儿童鼻腔鼻窦骨化纤维瘤诊治水平。方法1995年1月至2007年1月,对8例患儿的临床表现、治疗情况、病理检查及长期随访结果进行回顾分析并复习文献资料。结果本组8例患者中,男5例,女3例,年龄6～17岁,病程3个月～3年。肿瘤位于左侧面部4例,右侧面部4例。均行手术切除,鼻侧切开入路2例,内镜经鼻入路4例,犬齿窝入路配合鼻内镜手术2例。随访1.5～12年,6例无复发,术后半年复发1例, 1年复发1例,均经再次手术完整切除。结论骨化纤维瘤是一种良性骨肿瘤,临床常表现为颌面部无痛性膨大。影像学呈膨胀性生长,与周围组织有蛋壳样边界。病理显微镜下,胶原纤维呈漩涡状分布,其间散在分布不规则钙化团块,病变与周围骨皮质分界清楚。鼻内镜或内镜辅助下微创手术是唯一有效的治疗方法。OBJECTIVE To explore a much better method to diagnose and treat nasal and sinus ossifying fibroma （OF） in children. METHODS Eight patients with facial ossifying fibroma were studied retrospectively. Recent literature about this disease was also reviewed. RESULTS Of all patients there were 5 male and 3 female subjects, aged from 6 to 17 years old, history about 3 months and 3 years. The masses of 4 patients were on left face and other 4 patients on right face. All subjects were treated by operation. Lateral rhinotomy was applied in 2 cases; 2 cases in Caldwell- luc operation combined with nasal endoscopy; 4 cases in operation under nasal endoscope. 2 of all the cases were recurrent and recovered after the second operations. All patients were in good condition followed-up from 1.5 to 12 years. CONCLUSION Ossifying fibroma is a benign tumor which occurs much likely on face at teenagers. The tumor grows expansively and patients usually have no complaints wiht mass on face. CT scan or X-ray was helpful in determining the boundary of tumor. There is no special manifestation under microscope. Operation is the only effective and best therapy.

关 键 词：纤维瘤 骨化性 颌 儿童 

分 类 号：R739.62[医药卫生—肿瘤]