三维适形放疗治疗宫颈复发癌的临床观察  

Result of 3-dimensional conformal radiotherapy for recurrent cervical cancer

作　　者：马景光[1] 邢丽娜[1] 魏星[1] 刘晓[1] 

机构地区：[1]哈尔滨医科大学附属二院肿瘤放疗科,哈尔滨150086

出　　处：《临床肿瘤学杂志》2009年第6期551-553,共3页Chinese Clinical Oncology

摘　　要：目的:探讨三维适形放疗(3DCRT)治疗宫颈复发癌的疗效和毒性反应。方法:2003年10月～2006年11月共收治宫颈复发癌34例,采用3DCRT,总剂量50～65Gy。结果:所有患者均完成3DCRT治疗。获完全缓解(CR)为24.2%(8/33),部分缓解(PR)为45.4%(15/33),有效率(RR)为69.6%;疼痛缓解率为92.6%(31/41),出血完全缓解率为90.9%(10/11),生活质量明显改善,无治疗相关性死亡。中位生存期(OS)19.8个月;1、2、3年生存率分别为51.5%、24.2%和18.2%。结论:采用3DCRT治疗宫颈复发癌的疗效较好,可以提高局部控制率和延长生存期,并能提高生活质量,毒副反应亦可耐受。Objective：To explore the efficacy and toxic reaction of 3-dimensional confrumal radiotherapy（3DCRT） for recurrent cervical cancer. Methods： From October 2003 to November 2006, 34 patiants with recurrent cervical cancer were treated by 3DCRT of 50-65 Gy. Results：All of the patients had finished the 3DCRT. The total response,complete response rate and partial response rate were 69.6% ,24. 2% （8/33） and 45.4% （15/33） ,respectively. The medium overall survival was 19.8 mouths. The 1-,2- and 3-year survival rates were 51.5% ,24. 2% and 18.2%. The pain-alleviation rate was 92. 6% （31/41）. The hemorrhage control rate was 90. 9% （ 10/11 ）. Quality of llfe was improved without any treatment related death. Conclusion： Radiotherapy for recurrent cervical cancer is effective and well-tolerated,and it can promote locoregional control and prolong survival time.

关 键 词：宫颈癌 三维适形放疗 

分 类 号：R730.55[医药卫生—肿瘤] R737.33[医药卫生—临床医学]