MRI在乳腺癌新辅助化疗后行保乳手术中的应用  

Application of MRI in Breast-Conserving Surgery after Neoadjuvant Chemotherapy

作　　者：刘春萍[1] 潘华雄[2] 杨帆[3] 明洁[1] 黄韬[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院乳腺甲状腺外科,武汉430022 [2]华中科技大学同济医学院附属协和医院病理科,武汉430022 [3]华中科技大学同济医学院附属协和医院放射科,武汉430022

出　　处：《华中科技大学学报（医学版）》2009年第3期374-376,共3页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：湖北省卫生厅资助项目(No.3-172)

摘　　要：目的探讨磁共振成像(magnetic resonance imaging,MRI)在乳腺癌新辅助化疗后行保乳手术中的应用价值。方法回顾性分析该院2003年6月至2007年8月收治的38例经新辅助化疗后行手术治疗的乳腺癌患者的临床资料。所有病例在新辅助化疗前后均行MRI检查评估肿瘤大小,术后病理检查再次评估肿瘤大小。结果39.5%(15/38)肿瘤呈向心性缩小,其中10.5%(4/38)肿瘤向心性缩小周围无病灶残留,29.0%(11/38)肿瘤向心性缩小但周围仍有癌灶残留;60.5%(23/38)肿瘤呈筛状缩小。对肿瘤大小的评估,MRI检查肿瘤大小与病理切片呈正相关,相关系数为0.94(P<0.01)。结论MRI可以较准确评估新辅助化疗后残余肿瘤大小,在保乳手术中发挥重要作用。Objective To investigate the advantage of the application of magnetic resonance imaging （MRI） in evaluating the feasibility of breast-conserving surgery after neoadjuvant chemotherapy. Methods The clinical data of 38 patients with breast cancer receiving surgery after neoadjuvant chemotherapy during June 2003 to August 2007 were analyzed retrospectively. The size of the focus was evaluated by MRI before and after neoadjuvant chemotherapy. The pathological examination assessed the size again after surgery. Results Pathological examination indicated the foci of 15 patients （39.5%） had concentric reduction, with complete remission in 4 patients （10.5%） and residual foci in peripheral zone in 11 patients （29.0%）, and the foci of 23 patients （60.5%） responded in a sifter-like pattern. For the size of the focus, Pearson correlation coefficient between MRI and pathology was 0.94 （P〈0.01）. Conclusion MRI can assess the size of residual focus after neoadjuvant chemotherapy accurately, having great advantage in evaluating the feasibility of breast-conserving surgery.

关 键 词：磁共振成像 乳腺肿瘤 新辅助化疗 乳房切除术 区段 

分 类 号：R737.9[医药卫生—肿瘤]