尿酸与脂肪肝的关系探讨  

STUDY THE RELATIONSHIP OF URIC ACID WITH FATTY LIVER

作　　者：马先福[1] 王仁萍[1] 刘秋菊[2] 刘薇[1] 张积华[1] 袁梅[1] 

机构地区：[1]青岛大学医学院附属医院健康体检中心,青岛266003 [2]青岛大学医学院附属医院心外科

出　　处：《现代预防医学》2009年第13期2410-2412,共3页Modern Preventive Medicine

摘　　要：[目的]研究高尿酸血症与脂肪肝的危险因素及二者的相关性。[方法]运用流行病学调查方法调查987例脂肪肝患者的一般资料、尿酸等生化指标。[结果]①987例脂肪肝患者高尿酸血症392例,男女尿酸水平比较差异有统计学意义(t′=16.00,P﹤0.01),男性组41～50岁达峰值(31.19%);女性组51～60岁达峰值(21.68%);χ2检验差别具有统计学意义(χ2=90.14,χ2=129.31,P﹤0.01)。②多因素Logistic回归分析,饮酒、超重、高甘油三酯患者高尿酸血症相对危险度明显增高;饮酒、肥胖、高甘油三酯、高尿酸患者脂肪肝相对危险度明显增高。[结论]高尿酸血症及脂肪肝患者中青年多见,高尿酸血症与饮酒、超重、高甘油三酯呈正相关,脂肪肝与高尿酸血症、肥胖、高甘油三酯密切正相关。[Objective] To study high-risky factors of hyperuricemia and fatty liver and their relationship： [Methods] Used epidemiology method to investigate 987 eases of fatty liver. [ Results] （1）There were 392 hyperurieemia cases among 987 fatty liver cases. The uric acid level between male and female was obviously different （t＇=16.00, P〈 0.01）. The uric acid level of male patients aged 41-50 yeas old reached the peak （31.19%）, female aged 51-60 yeas old reached the peak （21.68%）. There was a significant difference through χ^2 test （χ^2= 90.14,χ^2 = 129.31, P 〈 0.01）. （2）Logistic tests indicated that the increase of hyperuricemia was related to alcohol drinking, obesity, hypertriglyceridemic. [Conclusion] Hyperuricemia and fatty liver cases are mainly middle-aged and young people. Hyperuricemia positively is correlated to alcohol drinking, obesity and hypertriglyeeridemie. Fatty liver is correlated positively to hyperuricemia, obesity, hypertriglyceridemic.

关 键 词：高尿酸血症 脂肪肝 流行病学 危险因素 

分 类 号：R575.5[医药卫生—消化系统]