前列腺穿刺活检胃肠道间质瘤1例报告并文献复习  

Gastrointestinal stromal tumor(GIST)examined by prostate needle biopsy:a case report and review of the literature

作　　者：祝清国[1] 赵亚昆[1] 刘伟[1] 高治忠[1] 

机构地区：[1]哈尔滨医科大学附属第二医院,黑龙江哈尔滨150086

出　　处：《现代肿瘤医学》2009年第7期1295-1297,共3页Journal of Modern Oncology

摘　　要：目的:探讨经前列腺穿刺活检证实胃肠道间质瘤(GIST)的临床应用。方法:报道一例经前列腺穿刺活检证实的GIST临床资料,并结合文献复习就其诊疗问题予以讨论。结果:活检标本经免疫酶组织化学证实为GIST,肿瘤组织巨大,未行手术治疗,应用酪氨酸激酶抑制剂伊马替尼治疗,随访12个月,患者仍存活,继续随访中。结论:经前列腺穿刺活检证实的GIST可能是前列腺或直肠部位的肿瘤,需手术切除标本方能确定。GIST与前列腺其他部位的肿瘤需通过免疫组化检查确定。完整的肿瘤切除并辅以伊马替尼是治疗GIST的有效手段。Objective ：To explore the clinical character of gastrointestinal stromal tumor（GIST） examined by prostate needlebiopsy. Methods： A ease of GIST on prostate needle biopsy was reported and some questions about this disease was discussed with reviewing related literatures, Results： The biopsy specimen was proved to be GIST through immuno - enzymohistochemistry, the tumor was too huge to be resected. Imatinib was used to treat with this tumor and in 12 months the patient was still alive. Conclusion： GIST proved by prostate needle biopsy may be in prostate or rectum,which can only be determined through resection sample. GIST should be differentiated from other stromal tumor of prostate, immuno - enzymohistochemistry is very useful. Complete resection of the tumor and imatinib are effective in treating GIST.

关 键 词：前列腺 胃肠间质瘤 伊马替尼 

分 类 号：R730.43[医药卫生—肿瘤]