恶性肿瘤细胞血循环微转移检测进展  

Development of blood circulation micrometastasis detection of cancer cells

作　　者：汪彬哲[1] 邓晓芳[1] 胡伟民[1] 

机构地区：[1]广州医学院附属肿瘤医院,广东广州510095

出　　处：《现代肿瘤医学》2009年第7期1378-1381,共4页Journal of Modern Oncology

基　　金：广东省医学科学技术研究基金项目(NO.A2007285)

摘　　要：恶性肿瘤是严重威胁人类健康的重要疾病之一,其致死的主要原因是肿瘤局部或区域的复发和远处转移。具有转移潜能的肿瘤细胞在术前或术时已脱离原发灶,以极少的数量转移到淋巴结、骨髓、血液或远处器官中,常规的检测手段却不能发现,称为肿瘤的微转移(micrometastasis)。肿瘤细胞血循环微转移是肿瘤远处器官转移的重要起始步骤。及时诊断肿瘤血循环微转移有助于治疗方案的选择及预后的判断。现就恶性肿瘤血循环微转移检测方法及目前研究进展作一综述。Cancer is one of the serious threats to human health. The mortality is mainly due to local or regional cancer recurrence and distant metastasis. Tumor ceils with metastatic potential in the preoperation have been out of the primary site. A small number of them have transferred to lymph nodes, bone marrow, blood or distant organs. Conventional means of detection can not find, the micro - called tumor metastasis （Micrometastasis）. Tumor cells circulating blood - transfer is an important initial step. Timely diagnosis of blood circulation micrometastasis is of great help to determine the clinical treatment programme and prognosis judgement. This paper reviewed the development of blood circulation micrometastasis detection of cancer cells

关 键 词：恶性肿瘤 外周血循环 微转移 PCR 

分 类 号：R730.3[医药卫生—肿瘤]