Methylseleninic Acid on The Apoptosis Induction and Invasion Inhibition in Human High-Meta-static Large Cell Lung Cancer Cell Line L9981  

作　　者：Jiewei LIU Yu FAN Li MA Jun CHEN Sen WEI Zhigang LI Hongyu LIU Haisu WAN Zhihao WU Qinghua ZHOU 

机构地区：[1]Tianjin Key Laboratory o fLung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University Hospital, Tianjin 300052, China

出　　处：《中国肺癌杂志》2009年第6期501-502,共2页Chinese Journal of Lung Cancer

基　　金：supported by a grant from the key project of the National Natural Science Foundation of China (to QinghuaZHOU)(No. 30430300);National Natural Science Foundation of China (to Qinghua ZHOU)(No. 30670922);INTERNATION Scienc and Techniquie COOPRATION PROGRAM OF CHINA (ISCP) (to Qinghua ZHOU)(No.2006DFB32330)

摘　　要：Background and Objective Lung cancer, which has been proved to have fastest increasing rate of morbidity and mortality, appears to be one of the most dangerous malignant tumor thatBackground and Objective Lung cancer, which has been proved to have fastest increasing rate of morbidity and mortality, appears to be one of the most dangerous malignant tumor that is threatening human being＇s health and lives. For recent 20 years, although researchers have dedicated themselves to the basic studies and clinical therapies on lung cancer, and managed to have many inspiring progresses, the total cure rate on lung cancer still tragically remains at about 15%. Therefore, searching for new anti-lung-cancer drugs, especially the one with high anti-cancer efficiency and low toxicity attracts increasingly more researchers. Selenium, as an essential element, plays an important role in physiological function as well as cancer prevention and therapy. Methylseleninic acid （MSA） is a kind of artificially developed selenium compound, which appears to be the best candidate for cancer prevention and/or therapy,

关 键 词：肺癌 癌细胞 扩散 化疗 

分 类 号：R734.2[医药卫生—肿瘤]