痉挛型双瘫患儿脑电图异常与认知功能的关系  

Relationship Between Electroencephalography Abnormality and Cognitive Impairment in Children with Spastic Diplegia Cerebral Palsy

作　　者：文香淑[1] 赖碧云[1] 邓富萍[1] 

机构地区：[1]珠海市妇幼保健院儿童神经康复科,广东珠海519001

出　　处：《实用预防医学》2009年第4期1153-1155,共3页Practical Preventive Medicine

摘　　要：目的分析痉挛型双瘫(双瘫)患儿脑电图异常和认知功能及影像学的关系。方法对99例痉挛型双瘫病例临床资料、影像和脑电图进行分析总结。单因素方差分析和卡方检验双瘫患儿脑电图正常、异常、癫痫样放电和癫痫发作和认知功能及影像学关系。结果双瘫脑电图正常组智力发育商(言语智商)平均87.87,异常组73.22,无发作癫痫放电组63.94,癫痫组60.44;运动发育商(操作商)分别为73.93、65.24、59.31和55.25。各组间差异有统计学意义(F=30.87、18.68,P均<0.01)。癫痫发病率为16.16%。影像改变和脑电图异常差异有统计学意义(χ2=27.14,P<0.01)。结论痉挛型双瘫患儿认知功能和脑电图异常及癫痫放电、是否合并癫痫有关;和脑损伤程度有关。Objective To study the cori＇elation between electroencephalography （EEG） abnormality and cognitive impairment in children with spastic diplegia cerebral palsy （CP）. Methods Clinical data, imaging and EEG of 99 children with spastic diplegia CP were analyzed and summarized. One - way ANOVA analysis and chisquare test were used tO examine the relationship between EEG abnormality and cognitive impairment. Results Vocabulary intelligence quotient （PIQ） or DQ of normal, abnormal EEG, epileptiform discharges, and epilepsy group were 87.87, ？3.22, 63.94, and 60.44, respectively. Permanforce IQ （DQ） was ？3.93, 6.5.24, 59.31, and 5.5.25, respectively. There were significant differences among the different groups （F = 30.87, F = 18.68, all P〈 0.01）. The frequency of epilepsy was 16.16 %. There were signif- icant differences between imaging and abnormal EEG （χ^2 = 27.14, P〈 0.01 ）. Conclusions There was a relationship between cognitive impairment and abnormal EEG, epileptiform discharge, with or without epilepsy, the brain damage degree in children with spastic diplegia CP.

关 键 词：痉挛型双瘫 脑电图 癫痫样放电 认知 

分 类 号：R741.044[医药卫生—神经病学与精神病学]