刺五加提取物对断奶仔猪血常规和抗氧化功能的影响  

Effects of Acanthopanacis senticosi Extract as Dietary Additive on Routine Blood and Antioxidant Parameters in Weaned Piglets

作　　者：孔祥峰[1] 刘合军[1] 尹富贵[1] 印遇龙[1] 柏美娟[1] 李铁军[1] 黄瑞林[1] 

机构地区：[1]中国科学院亚热带农业生态研究所动物生态营养与健康养殖联合实验室农业生态工程重点实验室,长沙410125

出　　处：《天然产物研究与开发》2009年第3期404-408,412,共6页Natural Product Research and Development

基　　金：中国科学院亚热带农业生态研究所青年人才领域前沿项目(ISACX-LYQY-QN-0703);中国科学院知识创新工程重要方向项目(Kscx2-Yw-N-022);国家十一五支撑计划项目(2006BAD12B07-6)

摘　　要：为研究日粮添加刺五加提取物对断奶仔猪血常规和抗氧化功能的影响,选择21日龄断奶仔猪60头,随机分为3个处理,每个处理20个重复,单栏饲养,分别饲喂基础日粮+0.1%刺五加提取物、基础日粮+0.02%粘杆菌素和基础日粮。于试验开始后第7、14和28d每个处理随机选取5头试猪,前腔静脉采血,测定血常规和抗氧化指标。结果表明:刺五加提取物能显著改善断奶仔猪的抗病能力,减轻应激反应,机体抗氧化酶活性明显升高;第7d时提取物组MID、PLT、MDA和NO含量显著小于基础日粮组(P<0.05);第14d时提取物组WBC显著小于、CAT活性显著大于基础日粮组(P<0.05);第28d时提取物组WBC、MID和GRA显著小于(P<0.05),SOD活性大于基础日粮组(P>0.05)。The experiment was conducted to determine the effects of Acanthopanacis senticosi extract as dietary additive on routine blood and antioxidant parameters in weaned piglets. A total of sixty piglets weaned at 21 days of age were randomly assigned to 3 treatment groups fed with maize and soybean meal-based diets containing 0 or 1 g/kg of Acanthopanacis senticosi extract, or 0.2 g/kg of colistin（ n = 20 per group）. On days 7,14, and 28 after the initiation of additive, five piglets were sampled randomly from each group. Blood sample （5 mL per piglet） was collected by venepuncture of vena jugularis for analysis of the routine blood parameters and antioxidant levels. Results showed that the extract significandy improved the ability of resist diseases, lighten the stress reactions, and increased the activities of antioxidant enzyme in the piglets. On day 7, the values of MID, PLT and NO were lower （P 〈 0.05 ） in the extract-supplemented piglets in comparison with the control group. Dietary additive with the extract reduced（ P 〈 0.05 ） WBC numbers ,while increased（P 〈 0.05 ） the activity of serum CAT on day 14 as compared with the control group. On day 28, the values of WBC, MID and GRA were lower（ P 〈 0.05 ） ,and the activity of SOD was higher（ P 〉 0.05 ） in the extract-supplemented piglets compared with the control group.

关 键 词：刺五加提取物 断奶仔猪 血常规 抗氧化功能 

分 类 号：Q946.91[生物学—植物学] R285.5[医药卫生—中药学]