外伤性白内障人工晶状体植入术后瞳孔膜形成观察与处理  

Clinical observation and management of pupil fibrous membrance formation after traumatic cataract extraction and posterior chamber intraocular lens implantation

作　　者：陈璐[1] 陈逖[1] 吴惠煌 

机构地区：[1]安徽医科大学附属医院眼科,230022

出　　处：《眼外伤职业眼病杂志》1998年第4期301-302,共2页Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries

摘　　要：目的探讨外伤性白内障人工晶状体植入术后瞳孔膜形成的机制及处理方法。方法对35例术后瞳孔膜形成的患者进行观察。Ⅰ级膜形成9眼，采用DXM眶内注射联合散瞳治疗。Ⅱ级膜形成26眼，采用5－Fu联合DXM眶内注射及散瞳术后随访3～6月。结果瞳孔膜1周内大部分吸收，2例10天吸收，无1例复发。结论瞳孔纤维膜的形成可能与血－房水屏障破坏和免疫反应有关。5－Fu联合DXM眶内注射及散瞳是治疗较严重瞳孔膜的有效方法。Objective To evaluate mechanism and management of pupil fibrous membrane formation after traumatic cataract extraction and posterior chamber intraocular lens (IOL) implantation. Methods We have observed 35 cases of pupil fibrous membrane formation, including 9 eyes of Ⅰ grade fibrous memberane formation and 26 eyes of Ⅱ grade, with intraorbital injection of Dexamethasone (DXM) combined mydriasis, and 5fluorouracil (5-Fu) and DXM combined mydriasis respectively. All of cases have followed up for 3-6 months. Results Fibrous membrane was absorbed within a week in 33 case, only 2 case,in the 10th.No are had a relapse. Conclusion It is suggested that there be a close relevance between the fibrous membrane formation and breakdown of blood-gqueous barrier and immune response. 5-Fu combined DXM introrbital injection and mydriasis are an effective method for treatment of serious pupil fibrous membrane formation.

关 键 词：外伤性 白内障 瞳孔膜 人工晶体植入术 

分 类 号：R776.105[医药卫生—眼科] R779.6[医药卫生—临床医学]