消化系统多器官粘膜相关淋巴组织淋巴瘤1例报道并文献复习  

MALT lymphoma of multiple organ in digestive system： a case was reported and associated articles were reviewed

作　　者：王志敢[1] 赵林[1] 张娜[2] 练亿香[1] 

机构地区：[1]湖南省长沙市中心医院病理科,410000 [2]湖南省长沙市第四医院病理科,410000

出　　处：《医学信息（下旬刊）》2009年第6期197-198,共2页Medical information

摘　　要：目的：探讨一例消化系统多器官粘膜相关淋巴组织淋巴瘤的临床病理特点，并复习有关文献。方法：结合有关临床资料，复习本病例所有HE切片，应用免疫组化法标记CD20、CD3、CD5、CD10、CD23、Cyclin D1、bcl-2和KI-67。结果：免疫表型CD20＋、bcl-2＋、CD23＋／-、KI-67＋，CD3-、CD-、CD10-、CyclinD1-，诊断为粘膜相关淋巴瘤。结论：结外粘膜相关淋巴瘤是一种低度恶性的B细胞淋巴瘤，其临床行为受淋巴细胞归巢的影响。Objective To study the clinical and pathologic characteristics of MALT lymphoma. The article was provided with a case of mucosa-associated lymphoid tissue lymphoma（MALT lymphoma） of multiple organ in digestive system, and associated articles were reviewed. Methods All HE sections of the case were reviewed,and the expression of CD20.CD3.CD5 .CD10.CD23 . CyclinD1 .bcl-2and KI-67 was studied by using immunohistochemistry（SP method）. The clinical data was also analysed. Resuits Positive expression of CD20.bcl-2.CD23.KI-67 and negative of CD3 .CD5 .CyclinD1 .CD10 is helpful in making a pathological diagnosis of MALT lymphoma . Conclusion MALT lymphoma of Extra-lymphnode is a kind of low-grade malignant B -cell lymphoma. Its clinic behavior is affected by lymphocyte homing.

关 键 词：多器官 粘膜相关淋巴组织 B细胞淋巴瘤 淋巴细胞归巢 免疫表型 诊断 鉴别 

分 类 号：R733.4[医药卫生—肿瘤]