微生态调节剂对机械通气患者肠内营养相关性腹泻的预防作用  

Prevention of micro-ecological preparation on enteral nutrition related diarrhea in patients with mechanical ventilation

作　　者：徐丽丹[1] 王传湄 刘西韶[1] 肖春莲[1] 赖小燕[1] 

机构地区：[1]广东省深圳市宝安区人民医院营养科,广东深圳518101

出　　处：《广东医学院学报》2009年第3期250-252,共3页Journal of Guangdong Medical College

摘　　要：目的观察微生态调节剂对机械通气患者肠内营养相关性腹泻的预防作用。方法89例机械通气患者随机分为试验组(n=44)和对照组(n=45)。两组患者均给予鼻饲瑞先肠内营养液,试验组加用鼻饲微生态调节剂1周。观察两组患者腹泻和菌群失调发生率、粪便中分泌型IgA(S-IgA)水平、肠内营养液达到目标供给量的时间。结果试验组腹泻和菌群失调发生率、肠内营养液达到目标供给量的时间均明显低于对照组(P<0.01),而鼻饲第8天粪便中S-IgA含量比对照组明显升高[(1.713±0.241)vs(1.567±0.193)g/L,P<0.01]。结论机械通气患者应用微生态调节剂可有效防止肠道菌群失调,减少腹泻发生,利于肠内营养治疗的顺利进行。Objective To study the preventive effect of micro-ecological preparation on enteral nutrition related diarrhea in patients with mechanical ventilation. Methods Eighty-nine patients with mechanical ventilation were randomly divided into treatment group （n =44）and control group （n = 45）. All patients received nasal feeding with enteral nutrition, but treatment group accepted additional micro-ecological preparation for 7 days. The occurrence of diarrhea and dysbacteria, fecal S-IgA, and the time to reach standard amount of enteral nutrition were observed. Results Compared with control group, the occurrence of diarrhea and dysbacteria, and the time to reach standard amount of enteral nutrition decreased, but fecal S-IgA level on day 8 increased in treatment group [（1.713±0.241） vs （1. 567±0. 193） g/L, P〈0.01]. Conclusion Micro-ecological preparation can prevent the alteration of intestinal flora, reduce the occurrence of diarrhea and enhance the administration of enteral nutrition in patients with mechanical ventilation.

关 键 词：微生态调节剂 机械通气 肠内营养 腹泻 

分 类 号：R151[医药卫生—营养与食品卫生学] R574.4[医药卫生—公共卫生与预防医学]