体复康对运动性疲劳大鼠海马组织中游离氨基酸的影响  

Effects of Tifukang on the Contentsof Free Amino Acidsin Hippocampal Tissue ofthe Rats with Sport Fatigue

作　　者：王天芳[1] 杨维益[1] 梁嵘[1] 李峰[1] 陈家旭[1] 胡加跃 董浩[1] 康纯洁[1] 刘晓兰[1] 刘燕[1] 高大安[2] 吕丹云 周未艾 王启荣 

机构地区：[1]北京中医药大学,北京100029 [2]国家体委体育科学研究所,北京100061

出　　处：《北京中医药大学学报》1998年第4期26-29,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家自然科学基金!(No.39430140)

摘　　要：观察了运动性疲劳模型动物海马组织中有关氨基酸的浓度及谷氨酸与γ氨基丁酸的比值（Ｇｌｕ／ＧＡＢＡ） 、芳香族氨基酸与支链谷氨酸的比值（ＡＡＡ／ＢＣＡＡ） 和酪氨酸等在运动前后的不同恢复时相点的变化，以及体复康对脑组织中氨基酸神经递质及脑中氨基酸代谢的调节作用。结果表明：中药体复康可调节因运动而引起的应激状态，使运动后动物的兴奋性经迅速降低的过程后恢复到运动前的状态，从而有利于机体内环境的调整及体力的恢复；在运动过程中，可使机体迅速处于应激状态，物质代谢增强，积极供能，有利于肌肉的持续运动；运动结束后，可使机体内环境迅速调整，使ＡＡＡ 含量减少，达到新的平衡，有利于运动后疲劳的消除。Ratsportfatigue model was usedin thestudy.Thechangesofratios of GLU/GABAand AAA/BCAA,and tyrosinecontentin hippocampaltissue, were determined in different restoring phases before and aftersport.Theregulating effects ofacompound TCMpreparation for mediating and nourishing qion amino acid neurotransmittersand amino acid metabolism in the brain, were observed .The resultsshowed thatthe compound TCM softcapsule,tifukang ,could regulatethe stressstate due to sports, make the decreased excitability of the animalaftersportsrestoretothelevelexisted beforesports,which was goodforregulating body○sinternalenvironmentandrestoringstrength.The results also showed that during sports, tifukang could put the animal quickly into stressstate,enhance substance metabolism and maintain continuous muscular movement;after sports, tifukang could quickly regulatethe animal○sinternalenvironment and decrease AAAcontentto a new equilibrium , which was goodfor dispersing fatigue and restoring strength .

关 键 词：体复康 运动性疲劳 游离氨基酸 中医药疗法 

分 类 号：R285.5[医药卫生—中药学]