直肠癌直肠系膜全切除术的临床病理依据及意义  

Clinicopathologic Evidence and the Significance for Total Mesorectal Excision in Rectal Cancer

作　　者：余永东 郑仰[2] 姚学清[3] 林锋[3] 

机构地区：[1]广东省陆丰人民医院外科,广东陆丰516500 [2]广东省汕头大学医学院,广东汕头510041 [3]广东省医学科学院,广东省人民医院胃肠肿瘤外科,广东广州510080

出　　处：《临床医学工程》2009年第7期1-3,共3页Clinical Medicine & Engineering

基　　金：广东省自然科学基金项目(项目编号:5301056);广东省人民医院科技项目基金(项目编号:Y2004009)

摘　　要：目的探讨直肠癌直肠系膜全切除术的临床病理依据。方法对102例具有较完整临床病理资料行直肠癌直肠系膜全切除术直肠癌组织、癌旁组织、直肠系膜进行常规病理切片,分析直肠系膜与直肠癌的分化程度、临床分期、淋巴结转移的关系及治疗效果。结果直肠系膜癌转移均与癌组织分化程度、临床分期、淋巴结转移有相关性(P<0.05)。结论直肠癌直肠系膜全切除术是治疗直肠癌的最佳途径,切除的直肠系膜的范围应根据Dukes分期、肿瘤的分化程度及肿瘤浸润肠壁的深度区别对待。Objective To discuss the clinicopathologic evidence for total mesorectal excision（TME） in rectal cancer. Methods Tissues of rectal cancer, tissues around the tumor and tissues of the mesorectum were all obtained from 102 patients who proceeded to TME procedure. Pathological sections were performed to analyze the relationship between the state of mesorectum and the differentiation, staging, lym- phadenopathy of rectal cancer, also analyze the effect of treatment. Results There was correlation（P〈0.05） between metastasis to mesorectum and the differentiation, staging, lymphadenopathy of cancer. Conclusions TME was the best of choice for the treatment of rectal cancer. The extent ofmesorectum to be excised depended on Dukes staging, differentiation and depth of infiltration of the tumor.

关 键 词：直肠癌 全直肠系膜切除术 病理 

分 类 号：R735.37[医药卫生—肿瘤]