蛛网膜下腔出血后脑血管痉挛的研究进展  

Progress of Cerebral Vasospasm After Subarachnoid Hemorrhage

作　　者：段鸿洲[1] 莫大鹏[1] 

机构地区：[1]北京大学第一医院神经外科

出　　处：《医学综述》2009年第15期2287-2291,共5页Medical Recapitulate

基　　金：高等学校博士学科点专项科研基金(20070001772)

摘　　要：脑血管痉挛是蛛网膜下腔出血后常见而危险的并发症，其导致的继发性缺血性脑损害是致死致残的主要原因。目前关于蛛网膜下腔出血引起脑血管痉挛的发病机制、诊断及治疗均为研究热点，且也是临床亟待解决的问题。但关于其确切的发病机制、诊断及治疗方法均未统一，尚存在较大争议。关于其发病机制学说，主要包括气体信号分子学说和炎性反应学说；目前对其诊断主要依赖脑血管造影、CT灌注成像、经颅多普勒超声等检查方法；针对其治疗，可采用药物治疗、脑脊液引流、血管内介入治疗或基因治疗等方法。本文就近期关于蛛网膜下腔出血后脑血管痉挛的形成机制、诊断及治疗的进展进行综述。Cerebral vasospasm （CVS）was a common and dangerous complication of subarachnoid hemorrhage（SAH） ,and its secondary ischemic brain injury is the main reason resulting in death and mutilation. This question is also suspending. There is a big disagreement among its pathogenesis, diagnosis and therapy. The pathogenesis mainly includes gas signal molecular theory and inflammatory theory. The diagnosis mainly depends on brai angiography, CT perfusion imaging, transcranial Doppler sonography, the therapy mainly fouced on medication, drainage of eerebrospinal fluid, vessel interventional therapy or gene therapy. This article reviews cerebral vasospasm after subarachnoid hemorrhage about its genesis mechanism, diagnosis and therapy.

关 键 词：蛛网膜下腔出血 脑血管痉挛 炎性因子 诊断 治疗 

分 类 号：R743.35[医药卫生—神经病学与精神病学]