^(18)F-FDG PET对肺癌及纵隔淋巴结转移的诊断价值  

The Role of ^(18)F-FDG PET for Diagnosis of Lung Cancer and Mediastinal Lymph Node Metastasis

作　　者：徐白萱[1] 关志伟[1] 陈英茂[1] 曹宝林[1] 姚树林[1] 田嘉禾[1] 

机构地区：[1]解放军总医院,北京100853

出　　处：《中国肿瘤》2009年第7期581-583,共3页China Cancer

基　　金：国家自然科学基金资助(00572003)

摘　　要：[目的]评价18F-FDGPET对肺癌诊断及纵隔淋巴结分期的作用。[方法]周围型肺部肿块患者109例,其中经病理证实的非小细胞肺癌(NSCLC)79例;健康体检300例。FDGPET显像后,目测和标准摄取值(SUV)相结合判断病灶良恶性,并与病理结果对照分析。[结果]PET显像对肺癌诊断的敏感性和特异性分别为89.8%和76.2%;对纵隔淋巴结分期的灵敏度和特异性分别为100.0%和95.7%;9.67%(年龄51～69岁)的健康体检者纵隔淋巴结高摄取。[结论]18F-FDGPET对肺癌诊断及分期有较高临床价值。结合年龄、病史及其它影像学检查进行综合判断十分重要。[Purpose] To investigate diagnostic value of ^18F-FDG PET in diagnosis and mediastinal lymph node staging of lung cancer. [Methods] One hundred and nine cases with indeterminated pulmonary mass were studied with whole-body ^18F-FDG PET imaging, among them 79 cases were pathologically proved as NSCLC. Three hundreds healthy controls were also studied. PET data were analyzed with standardized uptake value （SUV） and also with visualization. The results were compared with pathological results. [Results ] The sensitivity and specificity of PET were 89.9% and 76.2% respectively for diagnosis of lung cancer; 100.0% and 95.7% respectively for determing the metastatic mediastinal lymph nodes of NSCLC. The uptake of mediastinal lymph nodes was 9.67% in control group （51 to 69 years old）. [Conclusions] ^18F-FDG PET was valuable in diagnosis for lung cancer as well as staging. The diagnosis should be made by comprehensively analyzing

关 键 词：^18F—FDG PET 肺肿瘤 纵隔淋巴结 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]