非霍奇金淋巴瘤患者血清CA125、乳酸脱氢酶水平临床分析  

Clinical analysis of the serum CA125, LDH level in patients with non-Hodgkin lymphoma

作　　者：吴月兵[1] 于丁[1] 范玉华[1] 柯玉华[1] 

机构地区：[1]湖北省肿瘤医院肿瘤内科,武汉430079

出　　处：《白血病．淋巴瘤》2009年第7期410-411,共2页Journal of Leukemia & Lymphoma

摘　　要：目的探讨非霍奇金淋巴瘤（NHL）患者血清CA125、乳酸脱氢酶（LDH）水平与临床特点及CA125与LDH的相互关系。方法分析40例NHL患者治疗前血清CA125、LDH的变化。结果NHL患者血清CA125的升高与分期、分组、胸腹腔积液、IPI积分有关，CA125与LDH有较弱的正相关关系。结论血清CA125水平测定对NHL，特别是对伴胸腹腔积液的NHL诊断有重要的临床意义。Objective To investigate the level of serum cancer antigen 125 （CA125） and lactic dehydrogenase（LDH） and clinical features of patients with non-Hodgkin lymphoma（NHL）, and the correlation between the level of serum CA125 and LDH. Methods Forty patients with NHL were studied and the variances of the serum CA125, LDH level before treatment were analysed. Results A higher serum of CA125 was associated with clinical phase,group,hydrothorax and ascites,international prognostic index （IPI）, and had weaker positive correlation to LDH. Conclusion Measurement of serum CA125 had important clinical significance to the patients with NHL, especially to the patients with hydrothorax and ascites.

关 键 词：淋巴瘤 非霍奇金 肿瘤标记 生物学 CA125 乳酸脱氢酶 

分 类 号：R733.1[医药卫生—肿瘤]