男性乳腺癌的诊断和治疗  

Diagnosis and treatment of male breast cancer

作　　者：于泽平[1] 顾军[1] 

机构地区：[1]南京军区南京总医院解放军普通外科研究所,江苏南京210002

出　　处：《医学研究生学报》2009年第7期729-731,共3页Journal of Medical Postgraduates

基　　金：南京军区南京总医院科研基金资助项目(批准号:2005045)

摘　　要：目的:男性乳腺癌发病率明显低于女性,但治疗效果较差。目前,对男性乳腺癌的研究较少,文中探讨男性乳腺癌的临床特点、诊断、治疗及影响预后的因素。方法:对收治的2例和文献报道的409例男性乳腺癌患者临床资料进行回顾性分析。结果:所有患者均行手术治疗。乳腺癌的病理类型以浸润性非特殊型癌为主,雌、孕激素受体阳性的占多数。Ⅰ期患者65例(15.9%),所占比例较少,预后较好。Ⅱ期以上患者占多数为344例(84.1%),预后较差。结论:男性乳腺癌发病率低、发病年龄高、病程长、恶性程度高、预后差。治疗上应以手术为主,辅以放、化疗、内分泌治疗的综合治疗。Objective ： The morbility of male breast cancer is lower than female breast cancer. The treatment effectiveness of male breast cancer is worse than female breast cancer. There were fewer studies on male breast cancer. The aim of the paper was to study the clinical characteristics, diagnosis, treatment and the prognostic factors of male breast cancer. Methods： To analyze the clinical data of 2 cases of male breast cancer and 409 eases collected from past articles retrospectively. Results： All cases received surgery treatment. After operation, all cases were treated by adjuvant treatment including radiotherapy or/and chemotherapy or/and endocrine treatment. The major pathological type was infiltrative non-specific cancer. Estrogen receptor and progesterone receptor are positive in most cases. Cases in stage Ⅰ were fewer, more cases were in stage Ⅱ or stage m and stage Ⅳ. Prognosis are more better in stage Ⅰ patients than in stage Ⅱ, Ⅲ, Ⅳ patients. Conclusion ： Male breast cancer has the following clinical characteristics： lower incidence, older age, longer course, higher malignancy and poor prognosis. The operation combined with radiotherapy and chemotherapy and endocrine treatment was a better method to treat male breast cancer.

关 键 词：男性乳腺癌 诊断 治疗 预后 

分 类 号：R737.9[医药卫生—肿瘤]