^(13)C-呼气试验检测胃排空的原理及其结果分析  

Principle of ^(13)C-Breath Test and Analysis of Test Results in Evaluating Gastric Emptying

作　　者：黄晓璐[1] 曲新华[1] 蔡铭慈[1] 陈志威[1] 严惟力[2] 熊屏[1] 

机构地区：[1]上海交通大学医学院附属第九人民医院超声学科,200011 [2]上海交通大学医学院附属仁济医院核医学科

出　　处：《胃肠病学》2009年第6期375-377,共3页Chinese Journal of Gastroenterology

基　　金：国家自然科学基金(30770599);上海教委科技创新项目(09YZ82);上海交通大学医学院科研基金(2008XJ024)资助

摘　　要：随着稳定性核素^(13)C-呼气试验检测胃排空临床应用的普及,与其相关的问题也日益突出。作为一种间接测定胃排空的定量手段,理解试验原理和解读试验结果对临床工作者尤为重要。本文通过全面阐述^(13)C-呼气试验的原理、与其他胃排空检测方法的比较、试剂种类以及胃排空呼气试验底物^(13)C-辛酸和^(13)C-乙酸在体内的代谢以及^(13)C的转运和分布规律,以期能帮助临床工作者理解^(13)C-呼气试验的原理并分析试验结果。With the development and widespread use of stable nuclide ^13C-breath test in evaluating gastric emptying, its relative problems are emerging gradually. As an indirect quantifieational tool for measuring gastric emptying, it is important to understand the principle of ^13C-breath test and analyze the test results properly in clinical practice. This article aimed to elucidate the principle of ^13C-breath test, and to compare with the other gastric emptying methods, types of testing reagent, metabolism of breath test substrate ^13C-oetanoic/acetate acid, the transit and distribution of ^13C etc., so as to help the clinicians to understand the principle and results of ^13C-breath test.

关 键 词：放射性核素 呼气试验 胃排空 方法学 

分 类 号：R573[医药卫生—消化系统]