橙子对醉酒小鼠的解酒作用  

Study of the anti-alcohol effect of orange in mice

作　　者：乔宁[1] 刘斯佳[2] 周毅娟[1] 汤晔[1] 王丹[3] 

机构地区：[1]徐州医学院麻醉学院,2005级2班江苏徐州221004 [2]徐州医学院华方学院 [3]徐州医学院麻醉药理学教研室

出　　处：《徐州医学院学报》2009年第7期442-443,共2页Acta Academiae Medicinae Xuzhou

摘　　要：目的观察橙子对醉酒小鼠的解酒作用。方法将20只小鼠随机分为2组:生理盐水组(NS组)、橙汁组,每组10只。用38%乙醇溶液建立小鼠醉酒模型,醉酒后5 m in分别以生理盐水和橙汁灌胃,观察生理盐水和橙子对小鼠的解酒作用。结果用橙汁灌胃的小鼠醒酒时间比用生理盐水灌胃的小鼠醒酒时间短(P<0.05)。结论橙子对醉酒小鼠有解酒作用。Objective To investigate the anti - alcohol effect of orange in mice. Methods The mice were divided into two groups： NS group and orange group （n = 10 each）. Animal model of drunkenness was established with 38% alcohol solution. 5 rain after drunkenness, NS or orange juice was administered by gastric clysis to observe the effect of NS and oranges on the drunken mice. Results The time for soberness was longer with orange juice than with NS by intragastile administration for drunken mice （ P 〈 0.05 ）. Conclusion Orange can antagonize the effect of alcohol in mice.

关 键 词：橙子 乙醇 醉酒模型 解酒 小鼠 

分 类 号：R614.2[医药卫生—麻醉学]