63例老年眼附属器淋巴组织增生性疾病临床及病理分类研究  

A clinicopathological analysis of the classification ocular adnexal lymphoproliferative lesions in 63 elderly cases

作　　者：张志强[1] 杨建东[1] 范钦华[1] 曹丽[1] 刘宇[1] 洪瑾[1] 

机构地区：[1]中国人民解放军第81医院眼科,江苏南京210002

出　　处：《徐州医学院学报》2009年第7期452-454,共3页Acta Academiae Medicinae Xuzhou

摘　　要：目的分析老年眼附属器淋巴组织增生性疾病的临床特点及病理分类。方法回顾性分析60岁以上眼附属器淋巴组织增生性疾病63例患者的临床、病理资料,并予以分类。结果63例眼附属器淋巴组织增生性疾病中反应性淋巴组织增生7例(11.1%),不典型淋巴组织增生5例(7.9%),淋巴瘤51例(81.0%),各类型病变临床特征相似;51例眼附属器淋巴瘤中,有45例为黏膜相关淋巴组织边缘带B细胞淋巴瘤(MALT-EMZL)。结论老年眼附属器淋巴组织增生性疾病临床表现无特异性,大多数为低度恶性的淋巴瘤,病理检查是分类与鉴别诊断的主要依据,免疫组织化学技术能进一步明确诊断。Objective To explore the clinical features and histopathologic classification of ocular adnexal lymphoproliferative lesions in the elderly population. Methods The clinical and histopathologic data of 63 patients with ocular adnexal lymphoproliferative lesions were retrospectively analyzed. Results Of the 63 patients, 7 had reactive lymphoid hyperplasia （ 11.1% ）, 5 had atypical lymphoid hyperplasia （ 7.9% ） and 51 had the lymphoma （ 81.0% ）, with similar clinical features among a spectrum of disease entities. Of the 51 cases with lymphoma, 45 were found to have extranodal marginal zone B - cell lymphoma of mucosa - associated lymphoid tissue （ MALT - EMZL）. Conclusion There is no specificity in the clinical presentations of ocular adnexal lymphopraliferative lesions, most of which are low - grade malignant lymphomas. Histopathological examinations serve as the basis of the classification and differential diagnosis and of the ocular adnexal lymphoproliferative lesions in the elderly population, while immunohistochemistry can be employed to further make the definite diagnosis.

关 键 词：眼附属器 淋巴组织增生性疾病 MALT淋巴瘤 分类 

分 类 号：R777[医药卫生—眼科]