兔囊性动脉瘤模型静脉造影的应用经验  

Intravenous digital subtraction angiography of saccular aneurysm in rabbits:experience in its applying

作　　者：祝胜[1] 刘建民[1] 王奎重[1] 黄清海[1] 陆南[1] 

机构地区：[1]上海第二军医大学长海医院神经外科,200433

出　　处：《介入放射学杂志》2009年第7期518-520,共3页Journal of Interventional Radiology

基　　金：上海市自然科学基金(082R1404200)

摘　　要：目的评估经静脉DSA(IV-DSA)方法显示兔右侧颈动脉根部囊性动脉瘤模型形态的可行性,总结动脉瘤模型静脉造影法的经验。方法胰弹性蛋白诱导法建立10只兔右侧颈动脉根部动脉瘤模型,在同一体位和造影角度下对模型动物分别进行股动脉插管动脉造影和IV-DSA检查,测量动脉瘤各个径长,采用配对t检验的方法对比两种造影检查结果的差异。结果两种造影方法均能清晰显示动脉瘤模型的形态,测得动脉瘤及载瘤动脉各径长比较,差异无统计学意义(P均>0.05)。结论IV-DSA造影方法可较好的显示兔右侧颈动脉根部动脉瘤模型的形态,可作为动脉超选造影的补充方法。Objective To evaluate the feasibility of intra-venous digital subtraction angiography （IV- DSA） for visualizing the saccular aneurysm of right common carotid artery in rabbits and to summarize the practical experience. Methods Ten New Zealand white rabbits with elastase-induced saecular aneurysm model were involved in this study. Both intra-arterial digital subtraction angiography （IA-DSA） and IV-DSA via femoral artery were performed with the animal being kept at the same position and the tube at the same exposure angle. The size of neck, the height of aneurysm and the diameter of parent artery were measured, and the numerical values obtained from IV-DSA and IA-DSA were statistically compared by using paired t- test. Results The mean size of aneurismal neck, the height of aneurysm and the diameter of parent artery measured on IA-DSA were （4.23 ± 0.91 ） mm, （4.55 ± 1.45） mm and （3.91 ± 0.51） mm respectively, and that measured on IV-DSA were （4.21 ± 0.92） mm, （4.66 ± 1.40） mm and （3.93 ± 0.54） mm respectively. No significant difference in these numerical values existed between IA-DSA and IV-DSA （all P〉 0.05）. Conclusion IV-DSA can clearly visualize the saccular aneurysm of right common carotid artery and parent artery in rabbits, and it can be regarded as a complementary method to IA-DSA.

关 键 词：囊性动脉瘤 兔 经动脉数字减影血管造影 经静脉数字减影血管造影 血管影像 

分 类 号：R732.2[医药卫生—肿瘤] R-332[医药卫生—临床医学]