卒中诱导的免疫变化及相应治疗策略  

Stroke-induced immunological alterations and relevant treatment strategies

作　　者：陈燕婷[1] 徐运[1] 

机构地区：[1]南京大学医学院附属鼓楼医院神经科,210008

出　　处：《国际脑血管病杂志》2009年第6期440-443,共4页International Journal of Cerebrovascular Diseases

基　　金：国家自然科学基金（30470612）,江苏省科教兴卫工程医学重点人才项目（RC2007006）

摘　　要：卒中后免疫系统的变化主要包括脑组织局部炎症反应和全身性免疫变化。前者可加重卒中后脑损伤，后者加重感染易感性，继而影响脑功能恢复和预后。卒中干扰神经系统与免疫系统之问正常平衡关系的机制尚不清楚。文章就卒中诱导的免疫改变及其机制，以及临床可采取的相应治疗策略进行了综述。The changes of immune system following stroke mainly includes the local inflammatory responses of brain tissue and the systemic immunological changes. The former may exacerbate brain damage following stroke, the latter may increase the susceptibility to infection, and thus impact on brain function recovery and prognosis. Stroke interferes with the normal balance between the nervous system and the immune system, and its mechanism remains unclear.This article reviews the stroke-induced immunological alterations and their mechanisms, as well as the corresponding treatment strategies in clinical practice.

关 键 词：卒中 免疫学 治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学]