保留肾单位手术与根治性肾切除术治疗小肾癌疗效的对照研究  

Comparing study of therapeutic effect for treating small cell carcinoma by nephron-sparing surgery and radical nephrectomy

作　　者：李永生[1] 朱绍兴[1] 陈仕平[1] 许恩赐[1] 郑松[1] 蔡伟忠[1] 王彬[1] 翁明高[1] 卢庆[1] 

机构地区：[1]福建医科大学附属协和医院泌尿外科,福建福州350001

出　　处：《中华肿瘤防治杂志》2009年第13期1033-1035,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：评价保留肾单位手术与根治性肾切除术治疗小肾癌疗效,回顾性分析83例肿瘤直径≤4 cm的小肾癌手术治疗的效果,其中保留肾单位手术44例,根治性肾切除术39例。保留肾单位手术与根治性肾切除术相比,术中平均出血量、术后3 d引流量、并发症的发生率以及术后肿瘤复发和转移情况作为评价指标。结果两组患者均顺利完成手术。NSS组与RN组术中出血量分别为〔(130±11.5)mLvs(110±10.7)mL〕;术后3 d引流量两组分别为〔(110±8.6)mLvs(96±8.1)mL〕;并发症发生率(1/44vs1/39),两组之间差异无统计学意义。NSS组随访6～86个月(平均46个月),RN组随访8～86个月(平均48个月),均未发现局部复发和远处转移。初步研究结果提示,保留肾单位手术可以最大限度地保存残肾的肾单位和功能,是小肾癌患者有效和可靠的治疗方法,目前仍被认为是小肾癌治疗的金标准。The objective of this study was to evaluate the therapeutic effect for treating small cell carcinoma using nephron sparing surgery （NSS） and radical nephrectomy （RN）. Clinical data on 83 small cell carcinoma cases （44 NSS and 39 RN, R≤4 cm） were reviewed. Blood loss, draining volume, complications, rates of tumor recurrence and metastasis were comparatively studied. All the patients were performed smoothly. Blood loss [（130 ± 11.5） mL vs （110±10.7） mL], draining volume [（110±8.6） mL vs （96±8.1） mL], and complications （1/44 vs 1/39） were similar. The mean follow-up time of NSS and RN were 46（6-86） and 48（8-86） months. There were no tumor recurrence and metastasis in the two operation groups. The difference between the two groups was insignificant. In conclusion, Nephron-sparing surgery is as safe and effective as radical nephrectomy in patients with small renal cell carcinoma. It could maximally preserve the nephron and its function. It is regarded as the gold standard for small renal cell carcinoma till now.

关 键 词：肾肿瘤/外科学 肾单位 肾切除术/方法 

分 类 号：R737.11[医药卫生—肿瘤]