蒲公英蜂蜜对主动吸烟小鼠肺组织SOD的影响  

Protective effects of dandelion honey on initiative sigarette smoking induced pulmonary injury in mice

作　　者：赵华[1] 吴铁[1] 

机构地区：[1]广东医学院药理教研室,广东湛江524000

出　　处：《中国热带医学》2009年第8期1621-1622,共2页China Tropical Medicine

摘　　要：目的观察蜂蜜对吸烟小鼠肺组织超氧化物歧化酶(SOD)的影响。方法昆明种小鼠,随机分为3组,即正常对照组,吸烟模型组,蒲公英蜂蜜组。正常对照组小鼠不吸烟,其余两组连续吸烟7周,1d2次,30min/次。蒲公英蜂蜜组给予蒲公英蜂蜜每d2次,同时正常组每天用蒸馏水作对照。7周后处死动物,右肺组织做成匀浆,检测肺组织匀浆中SOD含量。结果吸烟组小鼠肺部SOD活性明显降低,蒲公英蜂蜜组小鼠肺部的SOD活性增加。结论蒲公英蜂蜜对小鼠吸烟造成肺组织病理损害有保护作用,其作用机制可能和蒲公英蜂蜜在肺部发挥的抗氧化作用等有关。Objective To observe the protective effects of dandelion honey-extraction on cigarette smoking-induced pulmonary injury in mice. Methods Kunming mice were randomly divided into 3 groups：healthy control group,model group and dandelion honey group.Except healthy control group,the others were exposed to cigarette smoking,bid,30 minutes/ day for 7 weeks.At the same time.the mice of dandelion honey group were given dandelion honey,bid for 7 weeks ,the mice of healthy control group were given distilled water.bid for 7 weeks.The pathologic changes of airways and lung tissues were determined.The active of SOD were measured. Results Cigarette smoking reduced the activity of SOD ain the model group,yet the activity of SOD increased in dandelion honey group. Conclusion Dandelion honey has the protective effect on cigarette smoking-induced injury.The mechanism may due to its antioxidation.

关 键 词：蒲公英蜂蜜 主动吸烟 小鼠 肺组织 超氧化物歧化酶 

分 类 号：R-332[医药卫生]