精神分裂症患者治疗前后执行和记忆功能的变化及意义  

Comparison of Executive and Memory Function Before and After Treatment in Patients with Schizophrenia

作　　者：彭红莉[1] 刘哲宁[2] 程明[1] 杨栋[1] 谌益华[1] 

机构地区：[1]湖南省脑科医院,湖南长沙410007 [2]中南大学精神卫生研究所,湖南长沙410011

出　　处：《医学临床研究》2009年第7期1200-1201,1204,共3页Journal of Clinical Research

摘　　要：【目的】探讨精神分裂症患者治疗前后认知功能障碍的变化及相关因素。【方法】比较32例已治愈的精神分裂症患者治疗前后的威斯康星卡片分类测验（WCST）、韦氏记忆测验评估（WMS）评定结果。【结果】精神分裂症患者治愈前后的WCST、WMS评分有显著差异（P〈0．01或P〈0．05）；进行相关分析，发现治疗前WCST、WMS评分与PANSS评分、病程、复发次数均无显著相关。【结论】精神分裂症患者治愈后认知功能得到很大改善。认知功能的损害与病程、复发次数、精神病症状无显著性相关。[Objectivel To explore the cognitive disorder and relative factors before and after treatment in schizophrenia. [Methods] All 32 schizophrenic patients were studied with Wechsler Memory Scale（WMS）, Wisconsin Card Sorting Test （WCST） before and after treatment. [Resultsl With paired t-test, the scores of WCST and WMS were obtained for all patients before and after treatment. The scores of PANSS before and after treatment, the illness duration, and the frequency of suffering had no relation to the scores of WCST and WMS. [Conclusion] The cognitive functions of the schizophrenic patients after treatment have been improved. The cognition disorders have no correlated with the illness duration, the frequency of suffering and the psychotic symptoms.

关 键 词：精神分裂症/治疗 记忆 

分 类 号：R749.3[医药卫生—神经病学与精神病学]