从痰瘀论治癫痫后认知功能障碍的临床研究  

Clinical Study on Cognitive Function Impairment of Patients with Epilepsy Based on the Theory of Phlegm and Blood Stasis

作　　者：胡跃强[1] 刘泰[1] 祝美珍[1] 胡玉英[1] 

机构地区：[1]广西中医学院第一附属医院神经内科,广西南宁530023

出　　处：《辽宁中医药大学学报》2009年第8期91-92,共2页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:评价根据痰瘀理论而组成的镇痫益智方对癫痫病人的认知功能的影响。方法:对2005年以来至我院癫痫门诊的36例患者中19例用西药抗癫痫药物卡马西平、苯妥英钠、托吡酯等治疗,17例在西药治疗的基础上加用中药镇痫益智方治疗,6个月后对两组对象进行智力测定,单纯西药治疗组还另外测定治疗前后的智力变化。结果:单纯西药治疗组治疗后平均IQ值为(81.64±11.78),加用中药治疗组治疗后平均IQ值为(89.83±17.23),两组比较P<0.05,差别有统计学意义;用单纯西药组治疗前智力测定平均IQ值为86.40±15.66,治疗后平均IQ值为(81.64±11.78),前后比较P<0.05,差别有统计学意义。结论:应用镇痫益智方治疗癫痫能改善患者的认知功能。Abstract： Objective ： To evaluate the effect of Chinese medicine zhenxianyizhi（ZXYZ） priscription formulated by the main principle of phlegm and blood stasis on cognitive function impairment of patients with epilepsy. Methods ： 36 cases suffering from epilepsy were chosen, of them 19 cases received western medicine（AEDs） treatment and 17 cases underwent ZXYZ priscfiption treatment besides AEDs. The IQ value oi the two groupes were measured alter 6 months respectively.To the western medicine monotherapy group ,we also measured their changes in IQ both before and after they took the drugs. Results ： The mean IQ score was significantly higher in the Chinese medicine group（89.83 ± 17.23） than in the western medicine group（81.64± 11.78）,P〈0.05. To those patients only received western medicine,their mean IQ score was significantly higher before took the the drugs（86.40 ± 15.66）, than after treatment（81.64 ± 11.78）,P〈0.05. Conclusion： .An.tiepilep.sia western m.edicine dru. gs can affect the cognitive function,cause the descent of IQ. ZXYZ priscriptioncan improve cognitive function impairment of patients with epilepsy.

关 键 词：癫痫 镇痫益智方 认知功能 

分 类 号：R742.1[医药卫生—神经病学与精神病学]