宫颈癌前哨淋巴结活检的假阴性原因分析  

The Cause of False Negative Detection of Sentinel Lymph Node Biopsy by Methylene Blue in Cervical Carcinoma

作　　者：蒋燕明[1] 李立[1] 

机构地区：[1]广西医科大学第五附属医院柳州市人民医院,柳州545006

出　　处：《热带医学杂志》2009年第7期753-754,759,共3页Journal of Tropical Medicine

基　　金：广西卫生厅科技攻关项目(No.Z2006241)

摘　　要：目的探讨染料法识别宫颈癌前哨淋巴结(SLN)活检时出现假阴性的原因。方法选择49例早期宫颈癌患者,术前宫颈瘤周注射亚甲蓝,行广泛子宫切除+盆腔淋巴结清扫术;进行前哨淋巴结定位及病理学检查。结果SLN识别率为87.8%(43/49),灵敏度为81.8%,准确率为92%,假阴性率为18.2%。结论本组假阴性与肿瘤大小、淋巴转移的途径、术前放疗、病理检测方法有关。Objective To investigate the cause of false negative detection of sentinel lymph nodes（SLN） biopsy in cervical cancer identified by methylene blue injection. Methods Forty-nine patients with early stage cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy were included in the study. Methylene blue was injected before operation. SLNs were identified by the blue staining during the operation, then the SLNs were analysed. Results For SLN biopsy, the success rate was 87.8%, the sensitivity was 81.8%, the specificity was 92%, and the false negative rate was 15.2%. Conclusion The cause of false negative result is due to an extensive primary tumor, lymphatic metastasis way, pre-operation radiotherapy, the method of pathological examination.

关 键 词：宫颈癌 前哨淋巴结 假阴性 

分 类 号：R737.33[医药卫生—肿瘤]