急性脑梗死与超敏C反应蛋白的关系  

The relationship between highly sensitive creactive protein and acute cerebral infarction

作　　者：林晓东[1] 赵丽[1] 王学敏[1] 王海英[1] 田小卫[1] 李福学[1] 

机构地区：[1]河北省秦皇岛市第二医院神经内科,066600

出　　处：《中华脑血管病杂志（电子版）》2009年第1期17-19,共3页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

基　　金：秦皇岛市科学技术研究与发展计划项目(2008-20)

摘　　要：目的探讨急性脑梗死患者血清超敏C-反应蛋白(hs-CRP)水平变化与脑梗死部位、严重程度及预后的关系。方法测定120例急性脑梗死患者和90名健康人血清hs-CRP的含量,按脑卒中患者临床神经功能缺损程度评分标准对患者进行评分,分组比较。结果脑梗死组血清CRP水平明显高于正常对照组(P<0.01)。不同部位梗死患者血清hs-CRP水平比较没有差异。脑梗死轻、中、重型患者血清hs-CRP水平差异有统计学显著性(P<0.05)。血清CRP水平越高的脑梗死患者病情越严重,临床预后差。结论血清hs-CRP水平增高与脑梗死的发生和严重程度有密切关系,而与病变部位无关。Objective To investigate the changes of the serum level of highly sensitive C- reactive protein （hs-CRP） in patients with acute cerebral infarction and its relationship to the lesions, severity of cerebral infarction. Methods The serum level of hs-CRP in 120 patients and 90 healthy persons was determined. All the patients were scored by clinic neurological deficit scale, and compared in groups. Results The serum level of hs-CRP in the patients was significantly higher than that in normal controls （ P 〈 0.01）, between natiewtn with different lesion infarction-erum hs-CRP levels had no difference.it was significantly higher in the serious group than in the middle and mild groups （ P 〈 0.05 ）. Conclusions The serum level of hs-CRP is closely correlated with the severity of cerebral infarction. Had nothing to do with the lesion localion.

关 键 词：动脉粥样硬化 脑梗死 C-反应蛋白 病变部位 预后 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R541.4[医药卫生—临床医学]