青少年特发性脊柱侧凸患者出生时父母年龄与其侧凸类型及严重程度的关系  

The influence of the parental ages at birth on curve patterns and curve severity of adolescent idiopathic scoliosis

作　　者：王玉[1] 邱勇[1] 王斌[1] 孙旭[1] 朱泽章[1] 朱锋[1] 钱邦平[1] 刘臻[1] 李海波[1] 

机构地区：[1]南京大学附属鼓楼医院脊柱外科,南京市210008

出　　处：《中国脊柱脊髓杂志》2009年第8期593-596,共4页Chinese Journal of Spine and Spinal Cord

基　　金：江苏省自然科学基金资助课题(BK2007003)

摘　　要：目的：探讨青少年特发性脊柱侧凸（adolescent idiopathic scoliosis，AIS）患者出生时的父母年龄与AIS患者的侧凸类型、侧凸严重程度的关系。方法：选取来自华东地区初诊的AIS女性患者308例，年龄9．7-18．5岁，平均15．0岁。所有患者就诊时均记录患者性别、出生日期、初诊日期、侧凸节段、主弯Cobb角度数、分娩方式、胎位、是否早产及患者父母的出生日期。根据主弯Cobb角度数将所有患者分为3组，A组〈200；B组为200～39°；C组≥40。；根据侧凸类型将患者分为6组，单胸弯组（Ⅰ组），双胸弯组（Ⅱ组），胸腰双主弯组（Ⅲ组），胸腰弯组（Ⅳ组），腰弯组（Ⅴ组），三弯组（Ⅵ组）。结果：根据Cobb角分组后，A组（n=48）、B组（n=214）、C组（n=46）患者出生时的平均父亲年龄分别为27．5、26．7、27．0岁，平均母亲年龄分别为25．8、25．2、25．5岁，三组间均无统计学差异（P〉0．05）。根据患者侧凸类型分组后，Ⅰ组（n=72）、Ⅱ组（n=14）、Ⅲ组（n=127）、Ⅳ组（n=44）、Ⅴ组（n=30）、Ⅵ组（n=21）患者出生时的平均父亲年龄分别为27．0、26．6、26．5、27．7、27．0、27．0岁，各组平均母亲年龄分别为25．9、25．5、25．3、25．0、25．1、25-2岁，各组间无统计学差异（P〉0．05）。自然分娩组和剖腹产组平均Cobb角度数分别为29．7。和30．5。，胎位正常组和胎位异常组平均Cobb角度数分别为29．8°和29．9°，足月产组和早产组平均Cobb角度数分别为29．9°和29．5°，均无统计学差异（P〉0．05）。结论：AIS患者出生时的父母年龄与患者的侧凸类型及侧凸严重程度无显著相关性，提示AIS患者的侧凸类型及主弯Cobb角度数不受患者出生时的父母年龄的影响。Objective：To investigate whether the parental ages at birth of Chinese adolescent idiopathic scoliosis（AIS） patients can affect the curve patterns and curve severity.Method：A total of 308 AIS girls from East China were included in this study.The date of birth ,date of preliminary diagnosis ,state of delivery ,curve patterns and Cobb angles of the patients were recorded precisely.Their parental ages at birth of the patients were noted too.All patients were divided into 3 groups（group A,〈20°,B,20°-39°,C, ≥40°） according to Cobb angles,additionally all patients were divided into 6 groups according to curve patterns,group Ⅰ ,single thoracic （ST）, Ⅱ ,double thoraeic（DT）, Ⅲ ,double major（DM）, Ⅳ,thoracolumbar（TL）, Ⅴ ,lumbar（L）, Ⅵ ,triple major （TM）.Result：For group A（n=48）,B（n=214）,and C（n=46）,the mean paternal ages at delivery were 27.5,26.7 and 27.0 years respectively,and the mean maternal ages at delivery were 25.8,25.2 and 25.5 years respectively.The mean paternal ages at delivery of group Ⅰ （n=72）, Ⅱ （n=14）, Ⅲ （n=127）, Ⅳ （n=44）, Ⅴ （n= 30）,and Ⅵ （n=21） were 27.0,26.6,26.5,27.7,27.0,and 27.0 years respectively,and the mean maternal ages at delivery were 25.9,25.5,25.3,25.0,25.1,and 25.2 years respectively.The parental ages at delivery were similar （P〉0.05） among patients with different curve magnitude and curve patterns.The mean Cobb angles of the normal delivery and abdominal delivery groups were 29.7° and 30.5° respectively （P〉0.05）.As for fetal position,the mean Cobb angles of normal and abnormal groups were 29.8° and 29.9° respectively,which showed no significant difference （P〉0.05）,the same finding existed in the term birth and the immature birth groups,with the mean Cobb angles of 29.9° and 29.5° respectively （P〉0.05）.Conclusion：No signifieant correlation is found between the parental ages at birth of AIS patients and curve patterns and curve severity.

关 键 词：特发性脊柱侧凸 父母年龄 侧凸类型 侧凸角度 青少年 

分 类 号：R682.3[医药卫生—骨科学]