微小胃癌、小胃癌31例临床病理分析  

Clinicopathological analysis of 31 cases with minute gastric cancer and small gastric cancer

作　　者：汪春付[1,2] 潘文胜[1] 艾新波[1] 仲华[1] 李青松[1] 

机构地区：[1]浙江大学医学院附属第二医院消化科,浙江杭州310009 [2]第四军医大学唐都医院传染科,陕西西安710038

出　　处：《实用肿瘤杂志》2009年第4期389-392,共4页Journal of Practical Oncology

基　　金：浙江省卫生厅资助项目(编号:2007A093);公益性行业科研专项经费支持(编号:200802112)

摘　　要：目的探讨微小胃癌和小胃癌临床、独特的生长模式及病理组织学变迁的特点,利于选择治疗方案。方法对31例微小胃癌和小胃癌患者临床及病理资料回顾性分析。结果微小胃癌及小胃癌组占同期早期胃癌病例的10.6%;微小胃癌组、小胃癌组高、中分化型分别为72.7%、55.0%;黏膜内癌分别为81.8%、35.0%;微小胃癌组不伴淋巴结转移,小胃癌组淋巴结转移率为5%;两组脉管浸润均阴性;微小胃癌组、小胃癌组癌肿表层部与浸润部病理组织学同型性分别为90.1%、85.0%;微小胃癌组及小胃癌组浸润部较表层部分化程度趋向低下者9.7%,趋向高分化3.2%。结论微小胃癌组较小胃癌组高、中分化型比例高、浸润浅;小胃癌可出现淋巴结转移;随着肿瘤的发展,微小胃癌及小胃癌自表层部向浸润部发展,病理组织学多趋低分化变迁;绝大部分微小胃癌及半数以上(高、中分化型、无淋巴结转移、无脉管浸润者)的小胃癌,可选择内镜下微创治疗。Objective To investigate the clinicopatbological features of minute gastric cancer （M-EGC） and small gastric cancer （S-EGC）. Methods Thirty patients with M-EGC or S-EGC who admitted from January 2004 to December 2007 were enrolled in the study. The clinicopathological data of patients were analyzed retrospectively. Results M-EGC and S-EGC accounted for 10.6% of all early gastric cancer. The differentiated cancer in M-EGC was 72.7% ,which was higher than that in S-EGC group （55.0%）. The intramucosal cancer in M-EGC group was 81.8% ,much higher than that in S-EGC group （35.0%）. None of M-EGC patients had lymph node matastasis,however, 1 of 20 S-EGC patients had lymph node metastasis. Both groups had not blood vessel and lymphatic vessel invasion. In 90.1% of M-EGC and 85.0% of S-EGC,the histopathological type of superficial lesions and invasive fronts were identical. In 9.7% of the cancer differentiation degree in invasive fronts was lower than that in superficial lesions,while in 3.2% of the cancer the tendency was reverse. Conclusion The clinicopathological analysis suggests that endoscopic surgery can be chosen for most M-EGC cases and more than half S- EGC cases.

关 键 词：胃肿瘤/病理学 肿瘤浸润 淋巴转移 胃黏膜/病理学 回顾性研究 

分 类 号：R735.2[医药卫生—肿瘤]