血栓通联合纳洛酮治疗急性脑梗死30例疗效观察  

Xueshuantong combine with naloxone for the treatment of acute cerebral infarction

作　　者：常冬梅[1] 

机构地区：[1]山东省临沂市中医医院内三科,276002

出　　处：《内科》2009年第4期523-524,共2页Internal Medicine

摘　　要：目的观察血栓通联合纳洛酮治疗急性脑梗死的临床疗效。方法将60例进展型脑梗死患者随机分为常规治疗组(对照组)和血栓通联合纳洛酮治疗组(治疗组)各30例。分别对两组患者治疗前、治疗14d后的神经功能缺损及临床疗效进行评价。结果两组治疗后14d的神经功能缺损较治疗前均有明显改善(P<0.01),治疗组与对照组比较有显著性差异P<0.01。治疗14d后,治疗组总有效率(83.33%)明显高于对照组(66.67%),P<0.05。结论血栓通联合纳洛酮治疗急性脑梗死有良好疗效,值得临床推广应用。Objective To observe the efficacy of Xueshuantong combine with naloxone in the treatment of acute cerebral infarction. Methods 60 patients with acute cerebral infarction were randomly assigned to the conventional treatment group （control group） and Xueshuantong plus naloxone group （observation group）. Both groups were assessed with the severity of neurological impairment and clinical effectiveness before treatment and at day 14 pest-treatment. Results The severity of neurological impairment at day 14 post-treatment were considerably improved in both group in comparison with that before treatment （ P 〈 0.01 ） and the severity was significantly improved in the observation group than in the control group at day 14 post-treatment （ P 〈0.01 ）. The overall effective rate was 83.33% in the observation group demonslrating a marked difference compared with 67.67% of the control group （ P 〈 0.05 ）. Conclusion Xueshuantong combine with naloxone is effective in improving the impaired nerve functions due to acute cerebral infarction ,worthy of further clinical application.

关 键 词：急性脑梗死 血栓通 纳洛酮 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]