糜烂性胃炎的胃动力检测和评价  

Detection and evaluation of gastric motility for the patients with erosive gastritis.

作　　者：阳家长 徐追[2] 李章勇[2] 任超世[2] 刘纯伦[3] 

机构地区：[1]重庆市永川区人民医院,重庆402160 [2]重庆邮电大学生物医学工程中心,重庆400065 [3]重庆医科大学附属第一医院消化内科,重庆400016

出　　处：《中国实用内科杂志》2009年第8期710-713,共4页Chinese Journal of Practical Internal Medicine

基　　金：国家自然科学基金资助(No.60471041);重庆市卫生局科技项目(2008-2-92);重庆市教委科技项目(KJ080519)

摘　　要：目的研究糜烂性胃炎患者胃动力电-机过程变化和影响因素,选择糜烂性胃炎的胃动力特征参数。方法筛选2008年2月至6月重庆市永州区人民医院收治的30例糜烂性胃炎患者,通过谱分析方法,据主能量和支配频率将信号分类,对患者进行数据采集。胃电信号和胃阻抗信号的频率,功率谱、动态谱、节律、正常胃电和胃阻抗节律的功率等参数由系统提供。结果患者的胃动力参数,2～4 cpm功率比例为59.2±4.4,频率百分比为(70.4±25.5)%,频率变异系数0.182±0.059,功率变异系数为1.576±0.481,与正常人群比较具有显著性(P<0.05)。用药1周后,患者主诉症状还没有缓解,或者消除,但是患者胃电功率和频率变异系数前后对比差异有统计学意义(P<0.05),来源于阻抗信号的胃动力参数有变化趋势,但差异无统计学意义(P>0.05)。结论实验结果表明基于胃阻抗和同步胃电信号测量的综合应用可能提供一种无创的技术来研究和估计与糜烂性胃炎的生理和病理学情况一致的胃动力状况。Objective In order to investigate the comlex course of electricity and mechanism of erosive gastritis （EG） and its relative factors, and to extract gastric motility feature indexes. Methods 30 volunteers of erosive gastritis were selected. The signal processing device was designed by Chongqing University of Posts and Telecommunications. By the means of spectrum analysis technic ,the signals could be classified according to the dominant power and dominant frequency. Some indexes such as frequency of EGG and IGM,signal power spectrum and dynamic spectrum,the rates of rhythm and power fnr the normal EGG and IGM and so on could also be calculated. Results The power ralio in 2 - 4 cpm was 59. 2 ± 4. 4,the frequency ratio was 70. 4 ± 25.5, the frequency instability coefficient was 0. 182 ± 0. 059, and the power instability coefficient was 1. 576 ± 0. 481. The parameters changed signifcantly between health adult and patient （ P 〈 0. 05 ）, The experiments of gastric motility measurement and evaluation were executed including before teatment and a week after the treatment. The volunteers felt that the symptom did not disappeared. The feature of electrogastrogram changed significantly （such as power instability coefficient,frequency instability coefficient P 〈 0. 05 ）, otherwise those of impedance signal did not show significance （ P 〉 0. 05 ）. Conclusion The results of the experiments show that the method based on the synchronous measurement of EGG and IGM can provide a non-invasive way to investigate and evaluate erosive gastritis corresponding to gastrointestinal physiology and pathology conditions.

关 键 词：糜烂性胃炎 胃动力 胃阻抗 多分辨分析 胃电 

分 类 号：R5[医药卫生—内科学]