Metachronous bile duct cancer nine years after resection of gallbladder cancer  

作　　者：Hye Jin Joo Gi Hyun Kim Won Joong Jeon Hee Bok Chae Seon Mee Par Sei Jin Youn Jae Woon Choi Rohyun Sung 

机构地区：[1]Department of Internal Medicine, College of Medicine, Chungbuk National University,Gaeshindong 62, Heungdukgu, Cheongju 361-711, South Korea [2]Department of General Surgery, Chungbuk National University,Gaeshindong 62, Heungdukgu, Cheongju 361-711, South Korea [3]Department of Pathology, College of Medicine, Chungbuk National University,Gaeshindong 62, Heungdukgu, Cheongju 361-711, South Korea

出　　处：《World Journal of Gastroenterology》2009年第27期3440-3444,共5页世界胃肠病学杂志（英文版）

摘　　要：We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a welldifferentiated adenocarcinoma, with negative resection margins （T2NOM0, stage Ⅰ B）. Nine years later, during a follow-up examination, abdominal computed tomography and MRCP showed an enhanced 1.7 cm mass in the hilum that extended to the second branch of the right intrahepatic bile duct. We diagnosed this lesion as a perihilar bile duct cancer, Bismuth type Ⅲ a, and performed bile duct excision, right hepatic Iobectomy and Roux-en-Y hepaticojejunostomy. The histological diagnosis was a well-differentiated adenocarcinoma with one regional lymph node metastasis （TINIM0, stage Ⅱ B）. Twelve months after the second operation, the patient is well, with no signs of recurrence. This case is compared with 11 other cases of metachronous biliary tract cancer published in the world medical literature.We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a well-differentiated adenocarcinoma, with negative resection margins (T2N0M0, stageB). Nine years later,during a follow-up examination, abdominal computed tomography and MRCP showed an enhanced 1.7 cm mass in the hilum that extended to the second branch of the right intrahepatic bile duct. We diagnosed thislesion as a perihilar bile duct cancer, Bismuth type.

关 键 词：Biliary tree Metachronous double cancer Gallbladder cancer Hilar bile duct cancer 

分 类 号：R735.8[医药卫生—肿瘤]