Fulminant amoebic colitis during chemotherapy for advanced gastric cancer  

作　　者：Noboru Hanaoka Katsuhiko Higuchi Satoshi Tanabe Tohru Sasaki Kenji Ishido Takako Ae Wasaburo Koizumi Katsunori Saigenji 

机构地区：[1]Department of Gastroenterology, Kitasato University School of Medicine,2-1-1 Asamizodai, Sagamihara-City, Kanagawa 228-8520, Japan

出　　处：《World Journal of Gastroenterology》2009年第27期3445-3447,共3页世界胃肠病学杂志（英文版）

摘　　要：A 52-year-old man had bloody stools during chemo-therapy for gastric cancer. A colonoscopy revealed necrotizing ulcer-like changes. A biopsy confirmed the presence of amoebic trophozoites. Subsequently, peritonitis with intestinal perforation developed, and emergency peritoneal lavage and colostomy were performed. After surgery, endotoxin adsorption therapy was performed and metronidazole was given. Symptoms of peritonitis and colonitis resolved. However, the patient's general condition worsened with the progression of gastric cancer. The patient died 50 d after surgery. Fulminant amoebic colitis is very rarely associated with chemotherapy. Amoebic colitis should be considered in the differential diagnosis of patients who have bloody stools during chemotherapy.A 52-year-old man had bloody stools during chemotherapy for gastric cancer. A colonoscopy revealed necrotizing ulcer-like changes. A biopsy confirmed the presence of amoebic trophozoites. Subsequently, peritonitis with intestinal perforation developed, and emergency peritoneal lavage and colostomy were performed. After surgery, endotoxin adsorption therapy was performed and metronidazole was given. Symptoms of peritonitis and colonitis resolved. However, the patient＇s general condition worsened with the progression of gastric cancer. The patient died 50 d after surgery. Fulminant amoebic colitis is very rarely associated with chemotherapy. Amoebic colitis should be considered in the differential diagnosis of patients who have bloody stools during chemotherapy.

关 键 词：Fulminant amoebic colitis Gastric cancer CHEMOTHERAPY AMOEBIASIS 

分 类 号：R735.2[医药卫生—肿瘤]