改良羊膜移植在预防和治疗外伤性角膜穿孔中的应用  

Modified amniotic membrane overlay transplantation for preventing and treating traumatic cornea perforation

作　　者：曹丽[1] 王佳域[1] 杨建东[1] 范钦华[1] 陈倩[1] 

机构地区：[1]中国人民解放军第81医院眼科,中国江苏省南京市210002

出　　处：《国际眼科杂志》2009年第8期1585-1586,共2页International Eye Science

摘　　要：目的:探讨生物胶粘贴缝合双层羊膜遮盖防治外伤性角膜穿孔的可行性。方法:15例18眼角膜损伤患者实施双层羊膜移植,其中角膜穿孔者14眼,深层溃疡达角膜1/3基质以上者4眼。小片羊膜覆盖在溃疡或穿孔处,将生物胶滴于羊膜、角膜表面,并将大片羊膜迅速贴于角膜表面。10/0尼龙线间断缝合大片羊膜于结膜创缘及浅层巩膜上。结果:所有患者视力均优于术前。术中及术后未见特殊并发症。结论:双层羊膜粘贴缝合治疗和预防外伤性角膜穿孔,操作简单,效果显著。AIM, To study the feasibility of biological adhesive in fixation of two-layer amniotic membrane transplantation （AMT） for preventing and treating traumatic cornea perforation. METHODS： Two-layer AMT was performed on 15 patients（ 18 eyes） with corneal injury, 14 eyes with traumatic cornea perforation, and 4 eyes with severe corneal ulcer upward of 1/3 corneal matrix. A small piece of amniotic membrane was covered on the focus, and a large one on the whole cornea by biological adhesive. The large amniotic membrane was sutured interruptedly to the traumatic edge of conjunctiva and superficial sclera by 10/0 nylon suture line. RESULTS： Vision of all patients was improved. No specific complications were found in the operation and after operation. CONCLUSION ： Two-layer AMT by biological adhesive is a very effective method to treat and prevent traumatic cornea perforation,and operation is simple.

关 键 词：羊膜 移植 角膜穿孔 

分 类 号：R779.6[医药卫生—眼科]