颌骨中心性血管瘤介入栓塞治疗后的临床病理观察  

Clinicopathological Observations of Central Hemangioma of the Jaws Treated with Arterial Interventional Chemoembolization

作　　者：王天舒[1] 李伟忠[1] 王斌[1] 吴乃强[1] 赵彤 

机构地区：[1]第一军医大学附属南方医院口腔科,广州510515 [2]第一军医大学附属南方医院病理教研室,广州510515

出　　处：《临床口腔医学杂志》1998年第3期150-151,共2页Journal of Clinical Stomatology

摘　　要：本文总结了采用数字减影血管造影（DSA）介入栓塞技术治疗的6例颌骨中心性血管瘤病例，将采用此技术治疗后手术切除的组织进行病理学观察。结果显示：经介入治疗后，血管瘤腔窦内有血凝块，部分腔窦闭塞，血管内皮细胞变性、坏死（凝固性坏死为主）。局部纤维结缔组织增生，机化血凝块，并出现明显的炎症反应。电镜观察：介入治疗后，血管内皮细胞出现核固缩，胞浆水肿，空泡变性，线粒体水肿，细胞间失去正常的连结结构，细胞之间间隙增宽。证明数字减影血管造影（DSA）介入栓塞技术是治疗颌骨中心性血管瘤的一种行之有效的方法。Arterial interventional chemoembolizat ion (AIC) is an effective met hod in t he control ofbleeding of central hemangioma of the jaws(CHJ), or used as an excellent adjunctive therapy precedessurgical excision. In order to explore its therapedtical mechanism in CHJ, 6 cases with CHJ treated withAIC were studied to observe the pathological and ultrastructural changes. The results showed that, 2weeks later, most cavernous spaces filled with blood blot, lacuna vasorum imperforated, degenerationoccurred in vascular endothelial cells such coagulation necrosis, karyopoyknosis, vacuolar degeneration,etc. Inflammatory cells and fibro-connective tissue were also found in the vascular space. It is concludedthat the effect of AIC is mainly on destroying the vascular endothelial cell, imperforating lacuna vasorunand stimulating regeneration of fibro-connective tissue'

关 键 词：颌骨肿瘤 中心性血管瘤 介入疗法 栓塞疗法 

分 类 号：R739.820.5[医药卫生—肿瘤] R732.2[医药卫生—临床医学]