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作 者:蒋华[1,2] 王焕旭[1,2] 张康兰 谢萍[1,2] 姜莉华
机构地区:[1]济南军区总医院眼科 [2]济南市中心医院中心实验室
出 处:《中国实用眼科杂志》1998年第7期420-421,共2页Chinese Journal of Practical Ophthalmology
摘 要:为探讨急性原发性闭角型青光眼(PACG)及其小梁切除术后角膜内皮细胞(CEC)的形态计量学变化和临床意义。对36例PACG患者于小梁切除术前和术后3个月进行了角膜内皮细胞观察和图象分析。结果:与正常人相比,PACG患者CEC密度、形状系数明显减小,面积、周长、长径、变异系数增大(P<0.01)。无并发症的小梁切除术未使CEC发生形态计量学变化。而术后浅前房者与术前相比CEC密度和形状系数进一步减小。面积、周长、长径和变异系数进一步增大。结论:PACG患者CEC处于不稳定状态,应尽早控制眼压。Objective:To study the morphometric changes of the endothelium following trabeculectomy in primary angleclosure glaucoma(PACG)and to evaluate the clinicl significance of these changes.Methods:The corneal endothelial cells(CEC)of 36 patients with PACG were examined by specular microscopy and the morphology of the CEC were analysised by computerasisted image analysis system before and after trabeculectomy.Results:As compared to the normal controls,the CEC of PACG showed a obviously decreased cell density(D),figure coefficient(FC)(P<001)and an increased area(A),perimeter(Pe),long axis(L),coefficient of variation(CV)(P<001)Uncomplicated trabeculectomy didnt produce endothelial morphometric changes.But the patients with shallow anterior chambers postoperatively had a further decreased D,FC and a further increased A,Pe,L and CV.Conclusions:The CEC of PACG are in an unstable condition.The intraocular pressure should be controled as early as possible.As making a plan of trabeculectomy or carring out the operation,the prevention and treatment of shallow anterior chambers are very important for protecting the CEC.
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